PMID- 17580442
OWN - NLM
STAT- MEDLINE
DCOM- 20070720
LR  - 20220317
IS  - 1000-0607 (Print)
IS  - 1000-0607 (Linking)
VI  - 32
IP  - 1
DP  - 2007 Feb
TI  - [A study on the time-effect relationship in the treatment of bronchial asthma 
      with medicinal vesiculation therapy].
PG  - 53-7
AB  - OBJECTIVE: To compare the therapeutic effects of medicinal vesiculation performed 
      in the dog-days and ordinary-days, as well as "Xin"-days and "Geng"-days in the 
      treatment of bronchial asthma. METHODS: A total of 162 bronchial asthma patients 
      were divided into ordinary-days group (n = 80) and dog-days group (n = 82) 
      according to the time sequence. Plasters made up of Gansui (Radix Euphorbiae 
      Kansui), Baijiezi (Semen Sinapis Albae), Mahuang (Herba Ephedrae), Xixin (Herba 
      Asari), etc. were applied to Feishu (BL 13), Fengmen (BL 12), Dingchuan (EX-B 1), 
      Pishu (BL 20) Shenshu (BL 23), etc. during ordinary days (spring, summer, autumn 
      and winter), dog days (the 1st-, 2nd- and 3rd-10 day periods of the hot season) 
      for each group, once every 10 days and with 3 times being a therapeutic course. 
      After a course of treatment, the curative effect was assessed. Before and 5 days 
      after the treatment, venous blood samples were collected for detecting serum 
      immunoglobulin E (IgE), lymphocyte transformation rate (LTR) and the number of 
      eosinophile granulocytes (Eos) separately. In addition, other 80 asthma patients 
      were treated during "Geng"-days ( (n = 42) and "Xin"-days (n = 38) separately 
      with the same methods mentioned above. RESULTS: After one course of treatment, or 
      the 82 and 80 cases in dog-days group and ordinary-days groups, 35 (43%) and 
      31(39%) experienced marked improvement in clinical symptoms, 41 (50%) and 37 
      (46%) had an improvement, 6 (7%) and 12 (15%) failed, with the effective rates 
      being 93% and 85% respectively. After the treatment, serum IgE and Eos count of 
      the two groups decreased significantly (P < 0.01, 0.05), and LTR of the two 
      groups increased evidently (P < 0.01). No significant differences were found 
      between two groups in the therapeutic effect and the 3 biochemical indexes. In 
      other 80 asthma patients, of the 42 and 38 cases in "Geng"-days group and 
      "Xin"-days group, 23 (54.76%) and 17 (44.74%) experienced marked improvement in 
      their symptoms, 17 (40.47%) and 19 (50.00%) had an improvement, 2 (4.76%) and 2 
      (5.26%) failed, with the effective rates being 95.23% and 94.74% separately. No 
      significant difference was found between two groups in the therapeutic effect (P 
      > 0.05). CONCLUSION: Medicinal vesiculation therapy can effectively improve 
      asthma patients' clinical symptoms, lower serum IgE and Eos count and raise LTR 
      whenever performed in the ordinary days, dog days, "Xin" days or "Geng" days. 
      Thus, this therapy is applicable all year round.
FAU - Zhuang, Li-Xing
AU  - Zhuang LX
AD  - Department of Acu-moxibustion, First Affiliated Hospital of Guangzhou University 
      of Chinese Medicine, Guangzhou 510405, China. zhuanglixing@163.com
FAU - Zhao, Ming-Hua
AU  - Zhao MH
FAU - Yang, Jun-Jun
AU  - Yang JJ
FAU - Deng, Qian-Ping
AU  - Deng QP
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - China
TA  - Zhen Ci Yan Jiu
JT  - Zhen ci yan jiu = Acupuncture research
JID - 8507710
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - *Acupuncture Points
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Asthma/immunology/*therapy
MH  - Child
MH  - Child, Preschool
MH  - Eosinophils/physiology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/blood
MH  - Lymphocyte Activation
MH  - Male
MH  - *Medicine, Chinese Traditional
MH  - Middle Aged
MH  - Time Factors
EDAT- 2007/06/22 09:00
MHDA- 2007/07/21 09:00
CRDT- 2007/06/22 09:00
PHST- 2007/06/22 09:00 [pubmed]
PHST- 2007/07/21 09:00 [medline]
PHST- 2007/06/22 09:00 [entrez]
PST - ppublish
SO  - Zhen Ci Yan Jiu. 2007 Feb;32(1):53-7.