PMID- 1758201
OWN - NLM
STAT- MEDLINE
DCOM- 19920206
LR  - 20191021
IS  - 0341-2040 (Print)
IS  - 0341-2040 (Linking)
VI  - 169
IP  - 6
DP  - 1991
TI  - Treatment of chronic bronchitis with terbutaline inhaled from a cone spacer with 
      and without positive expiratory pressure.
PG  - 325-33
AB  - Patients with chronic bronchitis were randomly allocated to 4 weeks treatment 
      with terbutaline 0.5 mg inhaled through a cone spacer with an expiratory 
      resistance creating a positive expiratory pressure (+PEP group) or without (-PEP 
      group). The patients recorded their symptoms in a diary and peak expiratory flow 
      (PEFR) was measured before and after each inhalation. PEFR increased 
      significantly after inhaled terbutaline both with and without PEP. The mean 
      increase in PEFR after terbutaline inhalations was significantly greater (p less 
      than 0.0001) in the +PEP group (24 L/min) compared to the -PEP group (17 L/min). 
      The +PEP group had less sputum and less difficulty with coughing up sputum 
      compared to the -PEP group. This study showed a small but significant enhancement 
      of the bronchodilation and a beneficial effect on symptoms when inhalation of 
      beta-2-agonist was combined with PEP in patients with chronic bronchitis.
FAU - Christensen, E F
AU  - Christensen EF
AD  - Department of Respiratory Diseases, University Hospital of Aarhus, Denmark.
FAU - Dahl, R
AU  - Dahl R
LA  - eng
PT  - Clinical Trial
PT  - Comparative Study
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Lung
JT  - Lung
JID - 7701875
RN  - N8ONU3L3PG (Terbutaline)
SB  - IM
MH  - Bronchitis/*drug therapy/physiopathology
MH  - Chronic Disease
MH  - Forced Expiratory Volume/physiology
MH  - Humans
MH  - Masks
MH  - Middle Aged
MH  - *Nebulizers and Vaporizers
MH  - Peak Expiratory Flow Rate/physiology
MH  - Terbutaline/administration & dosage/*therapeutic use
MH  - Vital Capacity/physiology
EDAT- 1991/01/01 00:00
MHDA- 1991/01/01 00:01
CRDT- 1991/01/01 00:00
PHST- 1991/01/01 00:00 [pubmed]
PHST- 1991/01/01 00:01 [medline]
PHST- 1991/01/01 00:00 [entrez]
AID - 10.1007/BF02714169 [doi]
PST - ppublish
SO  - Lung. 1991;169(6):325-33. doi: 10.1007/BF02714169.