PMID- 17582346
OWN - NLM
STAT- MEDLINE
DCOM- 20070817
LR  - 20220227
IS  - 1074-7613 (Print)
IS  - 1074-7613 (Linking)
VI  - 26
IP  - 6
DP  - 2007 Jun
TI  - Development of dendritic-cell lineages.
PG  - 741-50
AB  - Dendritic cells (DCs) are a heterogenous population of bone-marrow-derived immune 
      cells. Although all DCs share a common ability to process and present antigen to 
      naive T cells for the initiation of an immune response, they differ in surface 
      markers, migratory patterns, localization, and cytokine production. DCs were 
      originally considered to be myeloid cells, but recent findings have demonstrated 
      that DCs can develop not only from myeloid- but also from lymphoid-committed 
      progenitors. The common feature of the progenitors capable of developing into DCs 
      is the surface expression of Flt3 receptor. The development of different 
      populations of DCs is differentially regulated by various transcription factors 
      and cytokines. This review summarizes the recent advances made in the field of DC 
      development.
FAU - Wu, Li
AU  - Wu L
AD  - Immunology Division, The Walter & Eliza Hall Institute of Medical Research, 1G 
      Royal Parade, Parkville, Victoria 3050, Australia. wu@wehi.edu.au
FAU - Liu, Yong-Jun
AU  - Liu YJ
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Immunity
JT  - Immunity
JID - 9432918
RN  - 0 (Transcription Factors)
SB  - IM
MH  - Animals
MH  - *Cell Lineage/genetics
MH  - Dendritic Cells/*immunology
MH  - Humans
MH  - Lymphoid Tissue/cytology/immunology
MH  - Mice
MH  - Myeloid Cells/immunology
MH  - Skin/cytology/immunology
MH  - Transcription Factors/metabolism
RF  - 123
EDAT- 2007/06/22 09:00
MHDA- 2007/08/19 09:00
CRDT- 2007/06/22 09:00
PHST- 2007/06/22 09:00 [pubmed]
PHST- 2007/08/19 09:00 [medline]
PHST- 2007/06/22 09:00 [entrez]
AID - S1074-7613(07)00299-3 [pii]
AID - 10.1016/j.immuni.2007.06.006 [doi]
PST - ppublish
SO  - Immunity. 2007 Jun;26(6):741-50. doi: 10.1016/j.immuni.2007.06.006.