PMID- 17589544
OWN - NLM
STAT- MEDLINE
DCOM- 20070817
LR  - 20240109
IS  - 1474-1733 (Print)
IS  - 1474-1733 (Linking)
VI  - 7
IP  - 7
DP  - 2007 Jul
TI  - Intrinsic and cooperative antigen-presenting functions of dendritic-cell subsets 
      in vivo.
PG  - 543-55
AB  - Dendritic cells (DCs) comprise several subsets, and their roles in the 
      presentation of antigens derived from pathogens, vaccines and self tissues are 
      now beginning to be elucidated. Differences in location, life cycle and intrinsic 
      abilities to capture, process and present antigens on their MHC class I and class 
      II molecules enable each DC subset to have distinct roles in immunity to 
      infection and in the maintenance of self tolerance. Unexpected interactions among 
      DC subsets have also been revealed. These interactions, which allow the 
      integration of the intrinsic abilities of different DC types, enhance the ability 
      of the DC network to respond to multiple scenarios of infection.
FAU - Villadangos, Jose A
AU  - Villadangos JA
AD  - The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, 
      Parkville, Victoria 3050, Australia. villadangos@wehi.edu.au
FAU - Schnorrer, Petra
AU  - Schnorrer P
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
PL  - England
TA  - Nat Rev Immunol
JT  - Nature reviews. Immunology
JID - 101124169
SB  - IM
MH  - Animals
MH  - Antigen Presentation/*immunology
MH  - Cell Differentiation
MH  - Dendritic Cells/*classification/cytology/*immunology
MH  - Humans
MH  - Immune Tolerance/immunology
MH  - Lymphocytes/immunology
MH  - Models, Immunological
RF  - 138
EDAT- 2007/06/26 09:00
MHDA- 2007/08/19 09:00
CRDT- 2007/06/26 09:00
PHST- 2007/06/26 09:00 [pubmed]
PHST- 2007/08/19 09:00 [medline]
PHST- 2007/06/26 09:00 [entrez]
AID - nri2103 [pii]
AID - 10.1038/nri2103 [doi]
PST - ppublish
SO  - Nat Rev Immunol. 2007 Jul;7(7):543-55. doi: 10.1038/nri2103.