PMID- 17594286
OWN - NLM
STAT- MEDLINE
DCOM- 20081124
LR  - 20181113
IS  - 1729-0503 (Electronic)
IS  - 1680-6905 (Print)
IS  - 1680-6905 (Linking)
VI  - 7
IP  - 2
DP  - 2007 Jun
TI  - Expansion of HIV-1 screening and anti-retroviral treatment programs in a 
      resource-poor setting: results from a faith-based organization in Jos, Plateau 
      State, Nigeria.
PG  - 93-100
AB  - BACKGROUND: Until recently, availability of anti-retroviral therapy (ART) in 
      Nigeria has been limited to government and university based programs. Through the 
      United States' President's Emergency Plan For AIDS Relief (PEPFAR), additional 
      funding has become available for the treatment of HIV-positive patients. 
      OBJECTIVE: To report the expansion of HIV-1 screening, enrollment in an ART 
      program, and treatment outcomes over twelve months among HIV-positive patients at 
      a nonprofit, non-governmental faith-based clinic providing free and holistic care 
      in Jos City, Plateau State, Nigeria. DESIGN: This was a retrospective analysis of 
      HIV-1 screening and ART received by patients at Faith Alive Foundation Hospital 
      (FAFH). From January through December 2005, voluntary counseling and testing 
      (VCT) was freely available to all patients who requested it. Also beginning in 
      December 2004, HIV-1 infected patients were enrolled in an expanded HIV/AIDS 
      program at FAFH, where patients in clinical stages 3 or 4 based on World Health 
      Organization (WHO) clinical classification, or had a CD4(+) cell count of less 
      than 200/ml, were initiated on a simplified highly active ART (HAART) regimen 
      through PEPFAR funding. Data from the first six quarters of the FAFH-PEPFAR ART 
      program are presented here. Additionally, analysis of 645 patients who have 
      received ART for one year, including changes in CD4(+) cell count from baseline 
      is shown. RESULTS: In 2005, a total of 7672 persons received VCT and 3869 (50.4%) 
      HIV-1 positive results were found. From October 2004 to March 2006, the total 
      number of patients enrolled in the FAFH HIV/AIDS program rose from 1330 to 5946 
      people. Over the same period, the number of patients who received ART increased 
      from 302 to 1667. A majority of patients received an oral ART regimen consisting 
      of generic nevirapine, lamivudine, and stavudine. The number of patients 
      initiated on ART each quarter ranged from 57-578, and the number of deaths of 
      patients on ART was between 12 and 21 people per quarter. Analysis of 645 
      patients initiated on ART during the first quarter of the FAFH-PEPFAR ART program 
      revealed that the median CD4(+) cell count at baseline was 106/ml and the median 
      increase was 173/ml (median time of follow-up, 7.0 months). CONCLUSIONS: 
      Comprehensive HIV/AIDS care has been significantly expanded at FAFH, a free and 
      holistic medical center in Jos, Nigeria. Cumulative data from the first year of 
      this PEPFAR-funded ART program indicated that promising outcomes are achievable 
      through delivery of care at this faith-based medical center.
FAU - Lum, Hillary
AU  - Lum H
AD  - University of Wisconsin, School of Medicine and Public Health, Madison, WI, USA.
FAU - Isichei, Christian
AU  - Isichei C
FAU - Isichei-Wakili, Mercy
AU  - Isichei-Wakili M
FAU - Redfield, Robert
AU  - Redfield R
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Uganda
TA  - Afr Health Sci
JT  - African health sciences
JID - 101149451
RN  - 0 (Anti-Retroviral Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Ambulatory Care Facilities
MH  - *Anti-Retroviral Agents/therapeutic use
MH  - Child
MH  - Female
MH  - HIV Infections/*drug therapy/physiopathology
MH  - HIV-1/*isolation & purification
MH  - Health Resources/*supply & distribution
MH  - Humans
MH  - Male
MH  - Mass Screening/*organization & administration
MH  - Nigeria
MH  - *Organizations, Nonprofit
MH  - Religion
PMC - PMC1925274
EDAT- 2007/06/28 09:00
MHDA- 2008/12/17 09:00
PMCR- 2007/06/01
CRDT- 2007/06/28 09:00
PHST- 2007/06/28 09:00 [pubmed]
PHST- 2008/12/17 09:00 [medline]
PHST- 2007/06/28 09:00 [entrez]
PHST- 2007/06/01 00:00 [pmc-release]
AID - jAFHS.v7.i2.pg93 [pii]
AID - 10.5555/afhs.2007.7.2.93 [doi]
PST - ppublish
SO  - Afr Health Sci. 2007 Jun;7(2):93-100. doi: 10.5555/afhs.2007.7.2.93.