PMID- 1760243
OWN - NLM
STAT- MEDLINE
DCOM- 19920212
LR  - 20051116
IS  - 1042-2196 (Print)
IS  - 1042-2196 (Linking)
VI  - 3
IP  - 11
DP  - 1991 Nov
TI  - Chromosome 11q13 abnormalities in human cancer.
PG  - 413-20
AB  - Structural abnormalities affecting band q13 of chromosome 11 have been reported 
      in a variety of human tumors, particularly multiple endocrine neoplasia type 1 
      (MEN1), certain low-grade B-cell neoplasms, and a significant subset of breast 
      and squamous cell carcinomas. The perturbations of the region are also varied, 
      ranging from allele loss and deletions to specific translocations and DNA 
      amplification. Given their clinical relevance in classifying tumors and 
      identifying patients at increased risk, it is important to locate and 
      characterize the genes on which these aberrations impinge. Here we assess the 
      candidate genes identified thus far and the evidence that implicates them in 
      tumorigenesis.
FAU - Lammie, G A
AU  - Lammie GA
AD  - Imperial Cancer Research Fund Laboratories, Lincoln's Inn Fields, London, UK.
FAU - Peters, G
AU  - Peters G
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cancer Cells
JT  - Cancer cells (Cold Spring Harbor, N.Y. : 1989)
JID - 9000382
SB  - IM
MH  - *Chromosome Aberrations
MH  - Chromosome Fragility
MH  - *Chromosomes, Human, Pair 11
MH  - Gene Amplification
MH  - Genes, Tumor Suppressor
MH  - Humans
MH  - Neoplasms/*genetics
MH  - Oncogenes
MH  - Translocation, Genetic
RF  - 86
EDAT- 1991/11/01 00:00
MHDA- 1991/11/01 00:01
CRDT- 1991/11/01 00:00
PHST- 1991/11/01 00:00 [pubmed]
PHST- 1991/11/01 00:01 [medline]
PHST- 1991/11/01 00:00 [entrez]
PST - ppublish
SO  - Cancer Cells. 1991 Nov;3(11):413-20.