PMID- 17603973 OWN - NLM STAT- MEDLINE DCOM- 20070823 LR - 20071115 IS - 1548-5609 (Electronic) IS - 1548-5595 (Linking) VI - 14 IP - 3 DP - 2007 Jul TI - Quotidian hemodialysis and inflammation associated with chronic kidney disease. PG - e35-42 AB - The mortality rate of chronic dialysis patients in the United States is 24% per year per the 2006 United States Renal Data System. Although there have been marked improvements in dialysis technology, cardiovascular disease is the principal cause of mortality in end-stage renal disease patients. Inflammation and left ventricular hypertrophy both contribute to atherosclerosis. Hemodialysis 3 times a week is the most commonly used form of dialysis in the United States. The multicenter hemodialysis (HEMO) study hypothesized that an increase in dialysis dose and use of high-flux membranes would improve mortality and decrease morbidity. This study failed to show decreases in mortality. In other studies, however, there appears to be improved morbidity with more frequent dialysis including daily nocturnal hemodialysis and short-daily hemodialysis. The more frequent dialysis may have some beneficial effect on the inflammatory process that occurs in end-stage renal disease. FAU - Hamlett, Leslie AU - Hamlett L AD - Nephrology Section, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73104, USA. FAU - Haragsim, Lukas AU - Haragsim L LA - eng PT - Journal Article PT - Review PL - United States TA - Adv Chronic Kidney Dis JT - Advances in chronic kidney disease JID - 101209214 RN - 9007-41-4 (C-Reactive Protein) SB - IM MH - C-Reactive Protein/metabolism MH - Cardiovascular Diseases/etiology/*mortality/physiopathology MH - *Cause of Death MH - Female MH - Humans MH - Inflammation/*epidemiology/etiology MH - Kidney Failure, Chronic/diagnosis/mortality/*therapy MH - Kidney Function Tests MH - Male MH - Multicenter Studies as Topic MH - Oxidative Stress MH - Renal Dialysis/*methods/*mortality MH - Risk Factors MH - Survival Analysis MH - Time Factors MH - United States RF - 74 EDAT- 2007/07/03 09:00 MHDA- 2007/08/24 09:00 CRDT- 2007/07/03 09:00 PHST- 2007/07/03 09:00 [pubmed] PHST- 2007/08/24 09:00 [medline] PHST- 2007/07/03 09:00 [entrez] AID - S1548-5595(07)00050-X [pii] AID - 10.1053/j.ackd.2007.03.006 [doi] PST - ppublish SO - Adv Chronic Kidney Dis. 2007 Jul;14(3):e35-42. doi: 10.1053/j.ackd.2007.03.006.