PMID- 17610282 OWN - NLM STAT- MEDLINE DCOM- 20071015 LR - 20070731 IS - 1053-1807 (Print) IS - 1053-1807 (Linking) VI - 26 IP - 2 DP - 2007 Aug TI - TOF-MRA using multi-oblique-stack acquisition (MOSA). PG - 432-6 AB - PURPOSE: To alleviate the intrinsic limitation of current time-of-flight magnetic resonance angiography (TOF-MRA) techniques, which are insensitive to in-plane blood flow due to the flow saturation effect. MATERIALS AND METHODS: A multi-oblique-stack acquisition (MOSA) technique was proposed in this study to tackle this TOF problem by acquiring two or more TOF image stacks bearing different orientations. The MOSA approach was evaluated in human brain MR angiograms by integrating it with the widely used multiple overlapping thin-slab acquisition (MOTSA) technique. Two TOF image sets in different orientations were acquired using MOTSA. They were combined pixel-by-pixel by taking the maximum intensity value. Maximum intensity projection (MIP) was then performed, and the resulting MRA quality was assessed. RESULTS: The results demonstrated that MR angiograms obtained by MOSA-MOTSA were clearly improved compared to those acquired by conventional MOTSA in the same scan time. CONCLUSION: MOSA clearly demonstrates its advantage over conventional TOF acquisition in visualizing in-plane blood flows. CI - (c) 2007 Wiley-Liss, Inc. FAU - Wu, Ed X AU - Wu EX AD - Laboratory of Biomedical Imaging and Signal Processing, University of Hong Kong, Hong Kong. ewu@eee.hku.hk FAU - Hui, Edward S AU - Hui ES FAU - Cheung, Jerry S AU - Cheung JS LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Magn Reson Imaging JT - Journal of magnetic resonance imaging : JMRI JID - 9105850 SB - IM MH - Algorithms MH - Blood Flow Velocity MH - Brain/pathology MH - Cerebral Angiography/methods MH - Humans MH - Image Processing, Computer-Assisted MH - Imaging, Three-Dimensional MH - Magnetic Resonance Angiography/*methods MH - Magnetic Resonance Imaging/methods MH - Models, Statistical EDAT- 2007/07/05 09:00 MHDA- 2007/10/16 09:00 CRDT- 2007/07/05 09:00 PHST- 2007/07/05 09:00 [pubmed] PHST- 2007/10/16 09:00 [medline] PHST- 2007/07/05 09:00 [entrez] AID - 10.1002/jmri.20954 [doi] PST - ppublish SO - J Magn Reson Imaging. 2007 Aug;26(2):432-6. doi: 10.1002/jmri.20954.