PMID- 17610952
OWN - NLM
STAT- MEDLINE
DCOM- 20071214
LR  - 20071001
IS  - 0147-9571 (Print)
IS  - 0147-9571 (Linking)
VI  - 30
IP  - 5-6
DP  - 2007 Sep
TI  - Current knowledge on lower virulence of Reston Ebola virus (in French: 
      Connaissances actuelles sur la moindre virulence du virus Ebola Reston).
PG  - 391-8
AB  - Ebola viruses (EBOV) and Marburg virus belong to the family Filoviridae, order 
      Mononegavirales. The genus Ebolavirus consists of four species: Zaire ebolavirus 
      (ZEBOV), Sudan ebolavirus (SEBOV), Ivory Coast ebolavirus (ICEBOV) and Reston 
      ebolavirus (REBOV). Three species of ebolaviruses, ZEBOV, SEBOV, ICEBOV, and 
      Marburg virus are known to be extremely pathogenic in primates and humans and 
      cause severe hemorrhagic fever leading up to case fatality rate of some 90%, 
      while REBOV is thought to be pathogenic in Asian monkeys but not in African 
      monkeys and humans. Recent studies indicated several factors involved in 
      different virulence between African EBOV and REBOV. This article reviews the 
      history, epidemiology, and virulence of REBOV.
FAU - Morikawa, Shigeru
AU  - Morikawa S
AD  - Department of Virology 1, National Institute of Infectious Diseases, 4-7-1 
      Gakuen, Musashimurayama, Tokyo 208-0011, Japan. morikawa@nih.go.jp
FAU - Saijo, Masayuki
AU  - Saijo M
FAU - Kurane, Ichiro
AU  - Kurane I
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20070703
PL  - England
TA  - Comp Immunol Microbiol Infect Dis
JT  - Comparative immunology, microbiology and infectious diseases
JID - 7808924
SB  - IM
MH  - Africa/epidemiology
MH  - Ebolavirus/*pathogenicity
MH  - Hemorrhagic Fever, Ebola/*virology
MH  - Humans
MH  - Virulence
RF  - 39
EDAT- 2007/07/06 09:00
MHDA- 2007/12/15 09:00
CRDT- 2007/07/06 09:00
PHST- 2007/02/10 00:00 [received]
PHST- 2006/05/16 00:00 [accepted]
PHST- 2007/07/06 09:00 [pubmed]
PHST- 2007/12/15 09:00 [medline]
PHST- 2007/07/06 09:00 [entrez]
AID - S0147-9571(07)00055-0 [pii]
AID - 10.1016/j.cimid.2007.05.005 [doi]
PST - ppublish
SO  - Comp Immunol Microbiol Infect Dis. 2007 Sep;30(5-6):391-8. doi: 
      10.1016/j.cimid.2007.05.005. Epub 2007 Jul 3.