PMID- 17612311 OWN - NLM STAT- MEDLINE DCOM- 20070926 LR - 20151119 IS - 8755-0229 (Print) IS - 8755-0229 (Linking) VI - 22 IP - 6 DP - 2007 May-Jun TI - Managing difficult-to-treat asthma: Lessons from a center of excellence in allergy and asthma care. PG - 350-8 AB - One in four asthma patients may not have their condition adequately controlled despite being treated according to current practice guidelines, and these patients experience persistent symptoms, frequent exacerbations, and high healthcare utilization. The Allergy and Asthma Center, a recognized center of excellence in the treatment of allergy and asthma, is based on a patient-first philosophy, and this article explains how the practice operates and the importance of maintaining efficient office flow, implementing technology, and building a caring and dedicated staff Because asthma patients are often referred from primary care physicians, many present with difficult-to-treat disease. Even though many of these patients have received inhaled corticosteroids either alone or in combination with other medications, their condition still remains not well controlled. Serum total immunoglobulin E (IgE) is commonly elevated in patients with dfficult-to-treat asthma, and consequently, the IgE blocker omalizumab may be a viable option in this setting. FAU - Smits, William AU - Smits W AD - The Allergy and Asthma Center, 7230 Engle Road, Suite 300, Fort Wayne, IN 46804, USA. wlsmits@aol.com FAU - Letz, Kevin AU - Letz K LA - eng PT - Journal Article PL - United States TA - J Med Pract Manage JT - The Journal of medical practice management : MPM JID - 8605494 RN - 0 (Antibodies, Anti-Idiotypic) RN - 0 (Antibodies, Monoclonal) RN - 0 (Antibodies, Monoclonal, Humanized) RN - 2P471X1Z11 (Omalizumab) RN - 37341-29-0 (Immunoglobulin E) MH - Allergy and Immunology/*organization & administration MH - Ambulatory Care Facilities/*organization & administration/standards MH - Antibodies, Anti-Idiotypic MH - Antibodies, Monoclonal/therapeutic use MH - Antibodies, Monoclonal, Humanized MH - Asthma/*drug therapy/therapy MH - *Awards and Prizes MH - *Benchmarking MH - Drug Monitoring MH - Humans MH - Immunoglobulin E/blood/drug effects MH - Indiana MH - Medical Records Systems, Computerized MH - Omalizumab MH - Patient Satisfaction MH - Staff Development MH - Treatment Outcome EDAT- 2007/07/07 09:00 MHDA- 2007/09/27 09:00 CRDT- 2007/07/07 09:00 PHST- 2007/07/07 09:00 [pubmed] PHST- 2007/09/27 09:00 [medline] PHST- 2007/07/07 09:00 [entrez] PST - ppublish SO - J Med Pract Manage. 2007 May-Jun;22(6):350-8.