PMID- 17621355
OWN - NLM
STAT- MEDLINE
DCOM- 20071130
LR  - 20101118
IS  - 0148-639X (Print)
IS  - 0148-639X (Linking)
VI  - 36
IP  - 4
DP  - 2007 Oct
TI  - Transient decrease of sensory perception after thermoalgesic stimuli for 
      quantitative sensory testing.
PG  - 466-70
AB  - Transient decrease in the excitability of a reflex circuit following its 
      activation by appropriate stimuli is a well-recognized phenomenon, but it is 
      unclear how this applies to thermoalgesic stimuli during quantitative sensory 
      testing (QST). We examined the effects induced by a thermoalgesic (conditioning) 
      stimulus on the response to a subsequent (test) stimulus of the same 
      characteristics. All tests were done using a Peltier thermode with a surface area 
      of 12.5 cm(2) using ramp rates of 2 degrees C/s and variable interstimulus 
      intervals (ISIs) ranging from 10 to 60 s. Perception was measured with an 
      electronic visual analog scale. No changes were observed in latency of pain 
      perception. However, latency of warm perception was significantly delayed and 
      pain perception intensity was significantly reduced with respect to conditioning 
      stimuli at ISIs below 60 s. Our results indicate a transient saturation of warm 
      and heat pain perception systems after a thermoalgesic stimulus. We therefore 
      recommend that time intervals of >1 min be used between two consecutive 
      thermoalgesic stimuli when examining QST.
FAU - Schestatsky, Pedro
AU  - Schestatsky P
AD  - Department of Neurology, Hospital Clinic, Universitat de Barcelona, Villarroel 
      170, Barcelona, Spain.
FAU - Algaba, Rebeca
AU  - Algaba R
FAU - Perez, Daniel
AU  - Perez D
FAU - Casanova-Molla, Jordi
AU  - Casanova-Molla J
FAU - Leon, Lucia
AU  - Leon L
FAU - Costa, Joao
AU  - Costa J
FAU - Valls-Sole, Josep
AU  - Valls-Sole J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Muscle Nerve
JT  - Muscle & nerve
JID - 7803146
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Male
MH  - Pain Measurement/methods
MH  - Physical Stimulation/methods
MH  - Reaction Time/physiology/radiation effects
MH  - Sensory Thresholds/*physiology
MH  - *Temperature
MH  - Thermosensing/*physiology
EDAT- 2007/07/11 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/07/11 09:00
PHST- 2007/07/11 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/07/11 09:00 [entrez]
AID - 10.1002/mus.20837 [doi]
PST - ppublish
SO  - Muscle Nerve. 2007 Oct;36(4):466-70. doi: 10.1002/mus.20837.