PMID- 17625003
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20070905
LR  - 20181113
IS  - 1546-0096 (Electronic)
IS  - 1546-0096 (Linking)
VI  - 5
DP  - 2007 Jul 11
TI  - Involvement of dendritic cells in autoimmune diseases in children.
PG  - 16
AB  - Dendritic cells (DCs) are professional antigen-presenting cells that are 
      specialized in the uptake of antigens and their transport from peripheral tissues 
      to the lymphoid organs. Over the last decades, the properties of DCs have been 
      intensely studied and much knowledge has been gained about the role of DCs in 
      various diseases and health conditions where the immune system is involved, 
      particularly in cancer and autoimmune disorders. Emerging clues in autoimmune 
      diseases, suggest that dendritic cell dysregulation might be involved in the 
      development of various autoimmune disorders in both adults and children. However, 
      studies investigating a possible contribution of DCs in autoimmune diseases in 
      the pediatric population alone are scanty. The purpose of this review is to give 
      a general overview of the current literature on the relevance of dendritic cells 
      in the most common autoimmune conditions of childhood.
FAU - Lopez de Padilla, Consuelo M
AU  - Lopez de Padilla CM
AD  - Division of Rheumatology, Department of Medicine, Mayo Clinic College of 
      Medicine, Rochester, MN, USA. lopez.consuelo@mayo.edu
FAU - Reed, Ann M
AU  - Reed AM
LA  - eng
PT  - Journal Article
DEP - 20070711
PL  - England
TA  - Pediatr Rheumatol Online J
JT  - Pediatric rheumatology online journal
JID - 101248897
PMC - PMC1950864
EDAT- 2007/07/13 09:00
MHDA- 2007/07/13 09:01
PMCR- 2007/07/11
CRDT- 2007/07/13 09:00
PHST- 2007/05/02 00:00 [received]
PHST- 2007/07/11 00:00 [accepted]
PHST- 2007/07/13 09:00 [pubmed]
PHST- 2007/07/13 09:01 [medline]
PHST- 2007/07/13 09:00 [entrez]
PHST- 2007/07/11 00:00 [pmc-release]
AID - 1546-0096-5-16 [pii]
AID - 10.1186/1546-0096-5-16 [doi]
PST - epublish
SO  - Pediatr Rheumatol Online J. 2007 Jul 11;5:16. doi: 10.1186/1546-0096-5-16.