PMID- 17628288
OWN - NLM
STAT- MEDLINE
DCOM- 20071206
LR  - 20220410
IS  - 0278-5846 (Print)
IS  - 0278-5846 (Linking)
VI  - 31
IP  - 7
DP  - 2007 Oct 1
TI  - Residual symptoms in bipolar disorder: the effect of the last episode after 
      remission.
PG  - 1387-92
AB  - In this study it is aimed to assess interepisode residual symptoms in remitted 
      bipolar disorder patients with a hypothesis that the last episode recovered has 
      implications on residual symptomatology. The study was carried out with 23 
      bipolar patients diagnosed as mania (BP-M) and 20 bipolar patients diagnosed as 
      depression (BP-D) in their last episode, and with 22 healthy controls in a 
      university hospital clinic. All patients were in remission for at least 6 months. 
      In the assessment Hamilton Depression Rating Scale (HAM-D), Young Mania Rating 
      Scale (YMRS), Stroop Test, Auditory Verbal Learning Test (AVLT), increased 
      latency positive-evoked potentials (P300), Global Assessment of Functioning Scale 
      (GAF), and Social Functioning Scale (SFS) were used cross-sectionally. In 
      affective symptomatology, the BP-M group had higher YMRS scores, and the BP-D 
      group had higher HAM-D scores compared to the controls. P300 test results 
      revealed low amplitude in the BP-D group. In the AVLT, verbal learning and 
      delayed recall were significantly lower in the two bipolar groups. The Stroop 
      tasks were not different in the groups. Concerning the SFS, social withdrawal was 
      impaired in the two bipolar groups, whereas dependency-competency was impaired in 
      the BP-M and employment/occupation was impaired in the BP-D group. As a 
      conclusion, bipolar patients recovering from depressive episode may experience 
      more impairment in daily functioning due to residual depressive symptoms and 
      impairment of attention and memory.
FAU - Kaya, Ender
AU  - Kaya E
AD  - Department of Psychiatry, Ok Meydani State Hospital, Istanbul, Turkiye.
FAU - Aydemir, Omer
AU  - Aydemir O
FAU - Selcuki, Deniz
AU  - Selcuki D
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070614
PL  - England
TA  - Prog Neuropsychopharmacol Biol Psychiatry
JT  - Progress in neuro-psychopharmacology & biological psychiatry
JID - 8211617
RN  - 0 (Antimanic Agents)
RN  - 0 (Antipsychotic Agents)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Affect/physiology
MH  - Aged
MH  - Aged, 80 and over
MH  - Antimanic Agents/therapeutic use
MH  - Antipsychotic Agents/therapeutic use
MH  - Bipolar Disorder/*psychology
MH  - Cognition/physiology
MH  - Cognition Disorders/psychology
MH  - Depressive Disorder/psychology
MH  - Event-Related Potentials, P300/physiology
MH  - Female
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Neuropsychological Tests
MH  - Psychiatric Status Rating Scales
MH  - Social Adjustment
MH  - Social Behavior
MH  - Verbal Learning/physiology
EDAT- 2007/07/14 09:00
MHDA- 2007/12/07 09:00
CRDT- 2007/07/14 09:00
PHST- 2007/04/18 00:00 [received]
PHST- 2007/05/31 00:00 [revised]
PHST- 2007/06/06 00:00 [accepted]
PHST- 2007/07/14 09:00 [pubmed]
PHST- 2007/12/07 09:00 [medline]
PHST- 2007/07/14 09:00 [entrez]
AID - S0278-5846(07)00194-7 [pii]
AID - 10.1016/j.pnpbp.2007.06.003 [doi]
PST - ppublish
SO  - Prog Neuropsychopharmacol Biol Psychiatry. 2007 Oct 1;31(7):1387-92. doi: 
      10.1016/j.pnpbp.2007.06.003. Epub 2007 Jun 14.