PMID- 17628839
OWN - NLM
STAT- MEDLINE
DCOM- 20070806
LR  - 20071115
IS  - 1439-4413 (Electronic)
IS  - 0012-0472 (Linking)
VI  - 132
IP  - 30
DP  - 2007 Jul 30
TI  - [Reduction of in-hospital mortality and improved secondary prevention after acute 
      myocardial infarction. First results from the registry of secondary prevention 
      after acute myocardial infarction (SAMI)].
PG  - 1559-66
AB  - BACKGROUND AND OBJECTIVE: In hospital mortality of acute myocardial infarction 
      (AMI) has been reduced due to the availability of better therapeutic strategies. 
      But there is still a gap between mortality rates in randomised trials and daily 
      clinical practice. Thus, it was aim of the present registry to document the 
      course and outcome of patients with AMI and to improve patient care by 
      implementing recent guidelines. PATIENTS AND METHODS: In a nationwide registry 
      study in hospitals in Germany with a cardiology unit or an internal medicine 
      department data on consecutive patients were recorded for six to twelve months at 
      admission, discharge and during a follow-up of one year. RESULTS: From 02/2003 
      until 10/2004 a total of 5,353 patients with acute myocardial infarction (65.7 % 
      male, mean age of 67.6 +/- 17.7 years; 55.1 % of them with ST elevation 
      myocardial infarction (STEMI) were included in the registry. Of the patients with 
      STEMI, 76.6 % underwent acute intervention, 37.1 % had thrombolysis, 69.7 % 
      percutaneous transluminal coronary angioplasty (PTCA). 40.0 % of those with 
      non-Stemi (NSTEMI) had an acute intervention, 6.6 % thrombolysis, 73.5 % PTCA. 
      Recommended secondary prevention consisted of ASS (93.2 %), beta-blockers (93.0 
      %), CSE-inhibitors (83.5 %), ACE-inhibitors (80.9 %) and clopidogrel (74.0 %). 
      In-hospital mortality was 10.5 % (STEMI) and 7.4 % (NSTEMI). CONCLUSION: The 9 % 
      mortality among patients with acute myocardial infarction treated in the 
      hospitals participating in the SAMI registry is low compared to that in similar 
      collectives. The high number of patients who had thrombofibrinolysis and coronary 
      interventions as well as the early initiation of drug therapy contributed to 
      these results. Medical treatment in the prehospital phase of these patients 
      remains still insufficient and to a substantial extent contributes to the 
      mortality of acute myocardial infarction.
FAU - Tebbe, U
AU  - Tebbe U
AD  - Klinikum Lippe GmbH, Fachbereich Herz-Kreislauf, Detmold, Germany. 
      ulrich.tebbe@klinikum-lippe.de
FAU - Messer, C
AU  - Messer C
FAU - Stammwitz, E
AU  - Stammwitz E
FAU - The, G S
AU  - The GS
FAU - Dietl, J
AU  - Dietl J
FAU - Bischoff, K-O
AU  - Bischoff KO
FAU - Schulten-Baumer, U
AU  - Schulten-Baumer U
FAU - Tebbenjohanns, J
AU  - Tebbenjohanns J
FAU - Gohlke, H
AU  - Gohlke H
FAU - Bramlage, P
AU  - Bramlage P
CN  - SAMI Studiengruppe
LA  - ger
PT  - English Abstract
PT  - Journal Article
PT  - Multicenter Study
TT  - Ruckgang der Krankenhaus-Sterblichkeit und verbesserte Sekundarpravention nach 
      akutem Myokardinfarkt. Erste Ergebnisse des SAMI-Registers.
PL  - Germany
TA  - Dtsch Med Wochenschr
JT  - Deutsche medizinische Wochenschrift (1946)
JID - 0006723
RN  - 0 (Fibrinolytic Agents)
SB  - IM
MH  - Aged
MH  - Continuity of Patient Care/standards
MH  - Female
MH  - Fibrinolytic Agents/therapeutic use
MH  - Germany
MH  - *Hospital Mortality/trends
MH  - Humans
MH  - Male
MH  - Myocardial Infarction/*mortality/*prevention & control/therapy
MH  - Myocardial Reperfusion/methods
MH  - Patient Care/*standards
MH  - Practice Guidelines as Topic
MH  - Prognosis
MH  - Prospective Studies
MH  - *Quality of Health Care
MH  - *Registries
MH  - Time Factors
EDAT- 2007/07/14 09:00
MHDA- 2007/08/07 09:00
CRDT- 2007/07/14 09:00
PHST- 2007/07/14 09:00 [pubmed]
PHST- 2007/08/07 09:00 [medline]
PHST- 2007/07/14 09:00 [entrez]
AID - 10.1055/s-2007-984934 [doi]
PST - ppublish
SO  - Dtsch Med Wochenschr. 2007 Jul 30;132(30):1559-66. doi: 10.1055/s-2007-984934.