PMID- 17629933
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20181113
IS  - 1752-1947 (Print)
IS  - 1752-1947 (Electronic)
IS  - 1752-1947 (Linking)
VI  - 1
DP  - 2007 Jul 14
TI  - Atypical presentation of a middle age male with severe hypertriglyceridaemia: a 
      case report.
PG  - 51
AB  - BACKGROUND: Severe hypertriglyceridaemia (HTG) is uncommon but most prevalent in 
      subjects with type 2 diabetes mellitus (T2DM) and excess ethanol intake. CASE 
      PRESENTATION: We describe a case of a middle age male (53 y) presenting to the 
      emergency room with acute atypical central chest pain and severe HTG in the 
      absence of evidence of overt ischaemic heart disease (IHD). Admission ECG and EET 
      (exercise tolerance test) were negative for reversible ischaemic changes. His 
      admission glucose was 12.2 mmol/l, triglycerides (TG) were 103 mmol/l, total 
      cholesterol 37 mmol/l. Cardiac Troponin T could not be measured on three 
      occasions but CK MB mass was normal at 3 mug/l. The patient was started on 
      Bezafibrate 400 mg OD, Simvastatin 20 mg nocte, Omacor (Omega-3 fish oil) 1 gm bd 
      and Metformin 500 mg tds. Four weeks after admission, lipid and liver profiles 
      showed remarkable improvement, TG 2.9 mmol/l, Tchol 6.3 mmol/l and HDLc 1.5 
      mmol/l, ALAT and GGT were normal. CONCLUSION: A case report of severe 
      hypertriglyceridaemia with atypical presentation demonstrate the role of combined 
      lipid modifying agents in lowering triglycerides and cholesterol as well as 
      improving liver enzymes.
FAU - Albahrani, Ali I
AU  - Albahrani AI
AD  - Department of Clinical Biochemistry, St Mary's Hospital, Newport, Isle of Wight, 
      PO30 5TG, UK. ali.al-bahrani@iow.nhs.uk.
FAU - Usher J, Jannette
AU  - Usher J J
FAU - Marks, Eileen
AU  - Marks E
FAU - Ranganath, L
AU  - Ranganath L
FAU - Shenkin, Alan
AU  - Shenkin A
LA  - eng
PT  - Journal Article
DEP - 20070714
PL  - England
TA  - J Med Case Rep
JT  - Journal of medical case reports
JID - 101293382
PMC - PMC1963453
EDAT- 2007/07/17 09:00
MHDA- 2007/07/17 09:01
PMCR- 2007/07/14
CRDT- 2007/07/17 09:00
PHST- 2007/01/31 00:00 [received]
PHST- 2007/07/14 00:00 [accepted]
PHST- 2007/07/17 09:00 [pubmed]
PHST- 2007/07/17 09:01 [medline]
PHST- 2007/07/17 09:00 [entrez]
PHST- 2007/07/14 00:00 [pmc-release]
AID - 1752-1947-1-51 [pii]
AID - 10.1186/1752-1947-1-51 [doi]
PST - epublish
SO  - J Med Case Rep. 2007 Jul 14;1:51. doi: 10.1186/1752-1947-1-51.