PMID- 17632407 OWN - NLM STAT- MEDLINE DCOM- 20070906 LR - 20070716 IS - 0041-1337 (Print) IS - 0041-1337 (Linking) VI - 84 IP - 1 Suppl DP - 2007 Jul 15 TI - Tolerogenic functions of human leukocyte antigen G: from pregnancy to organ and cell transplantation. PG - S21-5 AB - Over the past few years, the number of publications concerning the human leukocyte antigen (HLA)-G molecule, its functions, and its pathological implications has greatly increased, largely exceeding those focusing simply on fetal-maternal activity. The role of this molecule in other situations of tolerance such as transplantation, tumor dissemination, or virus infections has also been reported. In this paper, we focus our attention on the relevance of HLA-G in transplantation in the light of recent data associating regulatory T cells and HLA-G, and which provide evidence of the role of HLA-G in improving graft acceptance. FAU - Rouas-Freiss, Nathalie AU - Rouas-Freiss N AD - Service de Recherches en Hemato-Immunologie, CEA-DSV-DRM, Hopital Saint-Louis, Institut Universitaire d'Hematologie, 1 Avenue Claude Vellefaux, 75010 Paris, France. nathalie.rouas-freiss@cea.fr FAU - Naji, Abderrahim AU - Naji A FAU - Durrbach, Antoine AU - Durrbach A FAU - Carosella, Edgardo D AU - Carosella ED LA - eng PT - Journal Article PL - United States TA - Transplantation JT - Transplantation JID - 0132144 RN - 0 (HLA Antigens) SB - IM MH - Animals MH - *Cell Transplantation MH - Female MH - Graft Rejection/immunology MH - HLA Antigens/*immunology MH - Humans MH - Immune Tolerance/*immunology MH - *Organ Transplantation MH - Pregnancy/*immunology MH - *Transplantation Immunology MH - Transplantation, Homologous/immunology EDAT- 2007/08/19 09:00 MHDA- 2007/09/07 09:00 CRDT- 2007/08/19 09:00 PHST- 2007/08/19 09:00 [pubmed] PHST- 2007/09/07 09:00 [medline] PHST- 2007/08/19 09:00 [entrez] AID - 00007890-200707151-00007 [pii] AID - 10.1097/01.tp.0000269117.32179.1c [doi] PST - ppublish SO - Transplantation. 2007 Jul 15;84(1 Suppl):S21-5. doi: 10.1097/01.tp.0000269117.32179.1c.