PMID- 17651006
OWN - NLM
STAT- MEDLINE
DCOM- 20071002
LR  - 20181113
IS  - 0898-929X (Print)
IS  - 1530-8898 (Electronic)
IS  - 0898-929X (Linking)
VI  - 19
IP  - 8
DP  - 2007 Aug
TI  - "I know you are but what am I?!": neural bases of self- and social knowledge 
      retrieval in children and adults.
PG  - 1323-37
AB  - Previous neuroimaging research with adults suggests that the medial prefrontal 
      cortex (MPFC) and the medial posterior parietal cortex (MPPC) are engaged during 
      self-knowledge retrieval processes. However, this has yet to be assessed in a 
      developmental sample. Twelve children and 12 adults (average age = 10.2 and 26.1 
      years, respectively) reported whether short phrases described themselves or a 
      highly familiar other (Harry Potter) while undergoing functional magnetic 
      resonance imaging. In both children and adults, the MPFC was relatively more 
      active during self- than social knowledge retrieval, and the MPPC was relatively 
      more active during social than self-knowledge retrieval. Direct comparisons 
      between children and adults indicated that children activated the MPFC during 
      self-knowledge retrieval to a much greater extent than adults. The particular 
      regions of the MPPC involved varied between the two groups, with the posterior 
      precuneus engaged by adults, but the anterior precuneus and posterior cingulate 
      engaged by children. Only children activated the MPFC significantly above 
      baseline during self-knowledge retrieval. Implications for social cognitive 
      development and the processing functions performed by the MPFC are discussed.
FAU - Pfeifer, Jennifer H
AU  - Pfeifer JH
AD  - Department of Psychology, University of California, Los Angeles, CA 90095, USA. 
      jenn.pfeifer@gmail.com
FAU - Lieberman, Matthew D
AU  - Lieberman MD
FAU - Dapretto, Mirella
AU  - Dapretto M
LA  - eng
GR  - RR00865/RR/NCRR NIH HHS/United States
GR  - RR13642/RR/NCRR NIH HHS/United States
GR  - MH075299/MH/NIMH NIH HHS/United States
GR  - F31 MH075299/MH/NIMH NIH HHS/United States
GR  - C06 RR012169/RR/NCRR NIH HHS/United States
GR  - M01 RR000865/RR/NCRR NIH HHS/United States
GR  - P41 RR013642/RR/NCRR NIH HHS/United States
PT  - Comparative Study
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, Non-P.H.S.
PL  - United States
TA  - J Cogn Neurosci
JT  - Journal of cognitive neuroscience
JID - 8910747
SB  - IM
MH  - Adult
MH  - Aging/physiology/psychology
MH  - Brain Mapping
MH  - Child
MH  - Gyrus Cinguli/physiology
MH  - Humans
MH  - Magnetic Resonance Imaging
MH  - Mental Recall/*physiology
MH  - Parietal Lobe/*physiology
MH  - Prefrontal Cortex/*physiology
MH  - *Self Concept
MH  - *Social Perception
PMC - PMC3407805
MID - NIHMS383071
EDAT- 2007/07/27 09:00
MHDA- 2007/10/03 09:00
PMCR- 2012/07/29
CRDT- 2007/07/27 09:00
PHST- 2007/07/27 09:00 [pubmed]
PHST- 2007/10/03 09:00 [medline]
PHST- 2007/07/27 09:00 [entrez]
PHST- 2012/07/29 00:00 [pmc-release]
AID - 10.1162/jocn.2007.19.8.1323 [doi]
PST - ppublish
SO  - J Cogn Neurosci. 2007 Aug;19(8):1323-37. doi: 10.1162/jocn.2007.19.8.1323.