PMID- 17651378
OWN - NLM
STAT- MEDLINE
DCOM- 20080422
LR  - 20080528
IS  - 1399-3038 (Electronic)
IS  - 0905-6157 (Linking)
VI  - 19
IP  - 2
DP  - 2008 Mar
TI  - Frequent IgE sensitization to latex, cow's milk, and egg in children with short 
      bowel syndrome.
PG  - 180-3
AB  - Children with short bowel syndrome (SBS) undergo frequent operations, so they are 
      at risk for sensitizing to latex. There have been isolated reports of 
      sensitization to food in these children. In a cross-sectional study, we assessed 
      sensitization to latex, cow's milk, and egg with skin prick tests (SPT) and 
      serum-specific immunoglobulin E (IgE) in 14 children with SBS. Data were 
      collected about the number of operations with latex devices, serum total IgE, and 
      history of feeding with milk formula. Ten children were sensitized to latex 
      (specific IgE median: 6.7 kU/l, range: 0.5-33). Compared with those 
      non-sensitized, sensitized children had significantly (p < 0.05) higher levels of 
      serum total IgE in z-units (mean rank 3.25 vs. 9.2, respectively), and more 
      operations with latex devices (mean rank 3.75 vs. 9). Eight children were 
      sensitized to cow's milk, one with only positive SPT, the other seven with 
      serum-specific IgE (median: 3.5, range: 0.5-21.1 kU/l), and five to egg (specific 
      IgE median: 0.68, range: 0.58-2.17 kU/l). Except for some isolated days with 
      cow's milk formula, the children had been initially fed with a diet without 
      intact cow's milk proteins. Sensitization to latex, cow's milk, and egg is very 
      frequent in children with SBS. They should be treated in a latex-free environment 
      since the very early stages of the disease, and should be routinely studied 
      regarding food sensitization, as this might contribute as an added factor in the 
      chronic diarrhea of these patients.
FAU - Mazon, Angel
AU  - Mazon A
AD  - Allergy Unit, Children's Hospital La Fe, Valencia, Spain. amazon@comv.es
FAU - Solera, Eva
AU  - Solera E
FAU - Alentado, Noemi
AU  - Alentado N
FAU - Oliver, Fernando
AU  - Oliver F
FAU - Pamies, Rafael
AU  - Pamies R
FAU - Caballero, Luis
AU  - Caballero L
FAU - Nieto, Antonio
AU  - Nieto A
FAU - Dalmau, Jaime
AU  - Dalmau J
LA  - eng
PT  - Journal Article
DEP - 20070725
PL  - England
TA  - Pediatr Allergy Immunol
JT  - Pediatric allergy and immunology : official publication of the European Society 
      of Pediatric Allergy and Immunology
JID - 9106718
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Child, Preschool
MH  - Comorbidity
MH  - Cross-Sectional Studies
MH  - Egg Hypersensitivity/diagnosis/*epidemiology/immunology
MH  - Female
MH  - Humans
MH  - Immunoglobulin E/*blood/*immunology
MH  - Latex Hypersensitivity/diagnosis/*epidemiology/immunology
MH  - Male
MH  - Milk Hypersensitivity/diagnosis/*epidemiology/immunology
MH  - Risk Factors
MH  - Short Bowel Syndrome/*epidemiology/immunology
MH  - Skin Tests/statistics & numerical data
EDAT- 2007/07/27 09:00
MHDA- 2008/04/23 09:00
CRDT- 2007/07/27 09:00
PHST- 2007/07/27 09:00 [pubmed]
PHST- 2008/04/23 09:00 [medline]
PHST- 2007/07/27 09:00 [entrez]
AID - PAI591 [pii]
AID - 10.1111/j.1399-3038.2007.00591.x [doi]
PST - ppublish
SO  - Pediatr Allergy Immunol. 2008 Mar;19(2):180-3. doi: 
      10.1111/j.1399-3038.2007.00591.x. Epub 2007 Jul 25.