PMID- 17661928 OWN - NLM STAT- MEDLINE DCOM- 20071128 LR - 20130520 IS - 0905-6947 (Print) IS - 0905-6947 (Linking) VI - 17 IP - 4 DP - 2007 Aug TI - The effect of ventilation strategies of child care centers on indoor air quality and respiratory health of children in Singapore. PG - 317-27 AB - This paper reports the effects of ventilation strategies on indoor air quality (IAQ) and respiratory health of children within 104 child care centers (CCCs) in a hot and humid climate. The CCCs were categorized by ventilation strategies: natural (NV), air-conditioned and mechanically ventilated (ACMV), air-conditioned using split units (AC), and hybrid (NV and AC operated intermittently). The concentration levels of IAQ parameters in NV CCCs are characterized by the influence of the outdoors and good dilution of indoor pollutants. The lower ventilation rates in air-conditioned CCCs result in higher concentrations of occupant-related pollutants but lower outdoor pollutant ingress. This study also revealed lower prevalence for most asthma and allergy, and respiratory symptoms in children attending NV CCCs. In multivariate analyses controlled for the effects of confounders, the risk of current rhinitis among children is significantly higher if they attend mechanically ventilated CCCs compared to NV CCCs. Air-conditioned CCCs were also associated with higher adjusted prevalence ratio of severe phlegm and cough symptoms and lower respiratory illness. Finally, children attending CCCs with hybrid ventilation are at high risk for almost all the respiratory symptoms studied. PRACTICAL IMPLICATIONS: This large field study indicates that different ventilation strategies employed by child care centers can cause significant variations in the indoor air quality and prevalence of asthma, allergies and respiratory symptoms of attending children. The higher prevalence rates of allergic and respiratory symptoms among young children, whose immune system is still under-developed, in child care centers, whether fully or partially air-conditioned, suggest that ventilation and plausible growth and propagation mechanisms of allergens and infectious agents be further investigated. FAU - Zuraimi, M S AU - Zuraimi MS AD - Department of Building, School of Design and Environment, National University of Singapore, Singapore. bdgzms@nus.edu.sg FAU - Tham, K W AU - Tham KW FAU - Chew, F T AU - Chew FT FAU - Ooi, P L AU - Ooi PL LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Indoor Air JT - Indoor air JID - 9423515 RN - 0 (Allergens) SB - IM MH - Air Conditioning MH - Air Pollution, Indoor/adverse effects/*prevention & control MH - Allergens/isolation & purification MH - Child MH - *Child Day Care Centers MH - Child, Preschool MH - Communicable Disease Control/methods MH - *Environmental Health MH - Humans MH - Infant MH - Respiratory Tract Diseases/epidemiology/etiology/*prevention & control MH - Risk Assessment MH - Singapore MH - Ventilation/*methods EDAT- 2007/07/31 09:00 MHDA- 2007/12/06 09:00 CRDT- 2007/07/31 09:00 PHST- 2007/07/31 09:00 [pubmed] PHST- 2007/12/06 09:00 [medline] PHST- 2007/07/31 09:00 [entrez] AID - INA480 [pii] AID - 10.1111/j.1600-0668.2007.00480.x [doi] PST - ppublish SO - Indoor Air. 2007 Aug;17(4):317-27. doi: 10.1111/j.1600-0668.2007.00480.x.