PMID- 17670756 OWN - NLM STAT- MEDLINE DCOM- 20080404 LR - 20101118 IS - 0195-668X (Print) IS - 0195-668X (Linking) VI - 28 IP - 19 DP - 2007 Oct TI - Field triage to primary angioplasty combined with emergency department bypass reduces treatment delays and is associated with improved outcome. PG - 2313-9 AB - AIMS: We investigated the net benefit in the outcome of reducing treatment delay through field triage and emergency department (ED) bypass in patients with ST-elevation myocardial infarction (STEMI) treated with primary angioplasty. METHODS AND RESULTS: In a prospective registry study, consecutive patients with suspected STEMI were assigned to: (i) pre-hospital ECG and triage or (ii) ECG and triage at the closest ED, solely based on ambulance availability. Four district hospitals and one regional heart centre serviced the 890,000 population metropolitan area and primary angioplasty was the only reperfusion strategy employed. Baseline characteristics were similar in STEMI patients triaged in the field (108) and the EDs (193). Symptom onset to balloon times: 154 [inter-quartile range (IQR) 120-233) vs. 249 (IQR 184-405) min (P<0.001) and peak creatine kinase in early presenters (<2 h): 1435 (95 %CI: 904-1966) U/L vs. 2320 (95% CI: 1881-2762) U/L (P=0.009) were lower in field- than in ED-triaged patients. Mortality in the PCI treated were 1.1 and 8.2% [P=0.025, RR 0.14 (95% CI: 0.01-1.08)] and overall mortality were 1.9 and 7.3% [P=0.046, RR 0.26 (95% CI: 0.05-1.11)]. CONCLUSION: Field-triage and ED bypass were feasible means of reducing treatment delay in patients with suspected STEMI and resulted in smaller infarct size in early presenters and a trend towards a reduction in mortality. FAU - Carstensen, Steen AU - Carstensen S AD - Department of Cardiology, Royal North Shore Hospital, University of Sydney, Australia. sc@dadlnet.dk FAU - Nelson, Greg C I AU - Nelson GC FAU - Hansen, Peter S AU - Hansen PS FAU - Macken, Lewis AU - Macken L FAU - Irons, Stephen AU - Irons S FAU - Flynn, Michael AU - Flynn M FAU - Kovoor, Pramesh AU - Kovoor P FAU - Soo Hoo, Soon Y AU - Soo Hoo SY FAU - Ward, Michael R AU - Ward MR FAU - Rasmussen, Helge H AU - Rasmussen HH LA - eng PT - Journal Article PT - Multicenter Study DEP - 20070801 PL - England TA - Eur Heart J JT - European heart journal JID - 8006263 SB - IM MH - Aged MH - Ambulances MH - *Angioplasty, Balloon, Coronary/mortality MH - *Coronary Angiography MH - *Electrocardiography MH - Feasibility Studies MH - Female MH - Humans MH - Male MH - Middle Aged MH - Myocardial Infarction/mortality/*therapy MH - Myocardial Reperfusion/methods MH - Prospective Studies MH - Time Factors MH - Treatment Outcome MH - Triage/*organization & administration EDAT- 2007/08/03 09:00 MHDA- 2008/04/05 09:00 CRDT- 2007/08/03 09:00 PHST- 2007/08/03 09:00 [pubmed] PHST- 2008/04/05 09:00 [medline] PHST- 2007/08/03 09:00 [entrez] AID - ehm306 [pii] AID - 10.1093/eurheartj/ehm306 [doi] PST - ppublish SO - Eur Heart J. 2007 Oct;28(19):2313-9. doi: 10.1093/eurheartj/ehm306. Epub 2007 Aug 1.