PMID- 17675735
OWN - NLM
STAT- MEDLINE
DCOM- 20070920
LR  - 20220321
IS  - 0973-3922 (Electronic)
IS  - 0378-6323 (Linking)
VI  - 73
IP  - 4
DP  - 2007 Jul-Aug
TI  - Type I lepra reaction presenting as immune reconstitution inflammatory syndrome.
PG  - 253-6
AB  - Immune reconstitution inflammatory syndrome (IRIS) is an unusual inflammatory 
      reaction due to infectious and non-infectious causes occurring in human 
      Immunodeficiency virus (HIV)-infected patients. IRIS occurs after the initiation 
      of antiretroviral therapy. There are no reports of type I lepra reaction due to 
      IRIS in published literature from India. We report two cases of HIV-infected 
      males who presented with borderline tuberculoid leprosy in type 1 reaction after 
      the initiation of highly active antiretroviral treatment (HAART). Case 1 
      presented with multiple, tender, erythematous and hypoesthetic plaques on the 
      trunk and extremities after 3 months of antiretroviral therapy. In case 2, type I 
      lepra reaction was observed 2 months after the initiation of HAART.
FAU - Kharkar, Vidya
AU  - Kharkar V
AD  - Department of Dermatology, Seth G. S. Medical College and KEM Hospital, Mumbai, 
      India. drvidyakharkar@gmail.com
FAU - Bhor, Urmila H
AU  - Bhor UH
FAU - Mahajan, Sunanda
AU  - Mahajan S
FAU - Khopkar, Uday
AU  - Khopkar U
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - Indian J Dermatol Venereol Leprol
JT  - Indian journal of dermatology, venereology and leprology
JID - 7701852
RN  - 0 (Leprostatic Agents)
SB  - IM
CIN - Indian J Dermatol Venereol Leprol. 2008 May-Jun;74(3):265-6. PMID: 18583802
MH  - AIDS-Related Opportunistic Infections/*chemically induced
MH  - Adult
MH  - Antiretroviral Therapy, Highly Active/*adverse effects
MH  - CD4 Lymphocyte Count
MH  - HIV Infections/complications/immunology
MH  - Humans
MH  - Hypersensitivity/diagnosis/*etiology
MH  - Leprostatic Agents/therapeutic use
MH  - Leprosy, Borderline/*chemically induced/diagnosis
MH  - Leprosy, Tuberculoid/*chemically induced/diagnosis
MH  - Male
MH  - Skin/pathology
MH  - Syndrome
EDAT- 2007/08/07 09:00
MHDA- 2007/09/21 09:00
CRDT- 2007/08/07 09:00
PHST- 2007/08/07 09:00 [pubmed]
PHST- 2007/09/21 09:00 [medline]
PHST- 2007/08/07 09:00 [entrez]
AID - 10.4103/0378-6323.33637 [doi]
PST - ppublish
SO  - Indian J Dermatol Venereol Leprol. 2007 Jul-Aug;73(4):253-6. doi: 
      10.4103/0378-6323.33637.