PMID- 17683786
OWN - NLM
STAT- MEDLINE
DCOM- 20071113
LR  - 20191210
IS  - 0361-9230 (Print)
IS  - 0361-9230 (Linking)
VI  - 74
IP  - 1-3
DP  - 2007 Sep 14
TI  - Single whisker experience started on postnatal days 0, 5 or 8 changes temporal 
      characteristics of response integration in layers IV and V of rat barrel cortex 
      neurons.
PG  - 29-36
AB  - Neonatal single whisker experience changes the response properties of spared 
      barrel neurons to deflections of principal and adjacent whiskers. However little 
      is known about the temporal characteristics of the paired whisker inputs. To 
      address this issue we used computer controlled mechanical displacement of paired 
      whiskers in control and plucked animals (plucking of all whiskers but D2 started 
      at 0, 5 and 8 postnatal days). The principal whisker (PW) and its caudal adjacent 
      whisker (AW) were deflected simultaneously or serially at different 
      inter-stimulus intervals (10, 20, 30, 50 and 100 ms). Neuronal responses were 
      recorded in D2 spared barrel both in layers IV and V. In the control group, 
      combined deflection of AW prior to PW led to suppression of ON and OFF responses 
      to PW deflection both in layers IV and V. The magnitude of this suppression was 
      strongly dependent on the inter-stimulus intervals (ISIs). At almost all tested 
      ISIs, whisker plucking from P0, P5 and P8 weakened suppressive interactions in 
      layers IV and V barrel neurons for both ON and OFF responses. The most decrease 
      in inhibitory interactions was observed in P5 plucked animals. Principal 
      whisker-evoked ON responses were increased only in P0 plucked animals both in 
      layers IV and V. AW-evoked ON responses are decreased in P5 plucked animals in 
      layer IV. The available data suggest that sensory experience can modulate 
      temporal aspects of response integration and receptive field properties of layers 
      IV and V neurons in barrel cortex. These changes have different critical periods.
FAU - Shamsizadeh, Ali
AU  - Shamsizadeh A
AD  - Department of Physiology, School of Medical Sciences, Tarbiat Modares University, 
      Tehran, Iran.
FAU - Sheibani, Vahid
AU  - Sheibani V
FAU - Arabzadeh, Somaye
AU  - Arabzadeh S
FAU - Afarinesh, Mohammad Reza
AU  - Afarinesh MR
FAU - Farazifard, Rasoul
AU  - Farazifard R
FAU - Noorbakhsh, S Mohammad
AU  - Noorbakhsh SM
FAU - Fathollahi, Yaghoub
AU  - Fathollahi Y
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070525
PL  - United States
TA  - Brain Res Bull
JT  - Brain research bulletin
JID - 7605818
SB  - IM
MH  - Action Potentials/physiology
MH  - Age Factors
MH  - Animals
MH  - Animals, Newborn
MH  - Conditioning, Psychological
MH  - Male
MH  - Neural Inhibition/physiology
MH  - Neuronal Plasticity/*physiology
MH  - Neurons/*physiology
MH  - Physical Stimulation/methods
MH  - Rats
MH  - Rats, Wistar
MH  - Sensory Deprivation/physiology
MH  - Somatosensory Cortex/*cytology/*growth & development
MH  - Statistics, Nonparametric
MH  - Time Factors
MH  - Vibrissae/*innervation
EDAT- 2007/08/09 09:00
MHDA- 2007/11/14 09:00
CRDT- 2007/08/09 09:00
PHST- 2006/11/12 00:00 [received]
PHST- 2007/03/14 00:00 [revised]
PHST- 2007/04/22 00:00 [accepted]
PHST- 2007/08/09 09:00 [pubmed]
PHST- 2007/11/14 09:00 [medline]
PHST- 2007/08/09 09:00 [entrez]
AID - S0361-9230(07)00134-7 [pii]
AID - 10.1016/j.brainresbull.2007.04.010 [doi]
PST - ppublish
SO  - Brain Res Bull. 2007 Sep 14;74(1-3):29-36. doi: 
      10.1016/j.brainresbull.2007.04.010. Epub 2007 May 25.