PMID- 17684419
OWN - NLM
STAT- MEDLINE
DCOM- 20080703
LR  - 20181201
IS  - 1423-0003 (Electronic)
IS  - 0304-324X (Linking)
VI  - 53
IP  - 6
DP  - 2007
TI  - Acute confusion or altered mental state: consider nonconvulsive status 
      epilepticus.
PG  - 388-96
AB  - BACKGROUND: The diagnosis of nonconvulsive status epilepticus (NCSE) is 
      particularly challenging in elderly patients. Confusion, personality change, 
      dysphasia, subtle motor activity and nystagmus may be the only presenting signs. 
      OBJECTIVE: To review current knowledge about NCSE with special focus on older 
      people. METHODS: Systematic review of the current literature via Medline search. 
      CONCLUSION: Although prospective studies are still lacking, NCSE may be one of 
      the most frequently missed diagnoses in patients presenting with altered mental 
      status. Elderly patients are at particular risk of diagnostic errors because of 
      the broad range of presentations of NCSE, significant comorbidities (especially 
      cerebrovascular disease), limited awareness of this particular seizure emergency 
      or difficulties with access to electroencephalography. Although diagnostic 
      criteria and treatment remain controversial, the diagnosis of NCSE is important 
      because it is potentially reversible.
CI  - Copyright 2007 S. Karger AG, Basel.
FAU - Beyenburg, Stefan
AU  - Beyenburg S
AD  - Department of Neurology, Centre Hospitalier de Luxembourg, Luxembourg, 
      Luxembourg, USA. beyenburg.stefan@chl.lu
FAU - Elger, Christian E
AU  - Elger CE
FAU - Reuber, Markus
AU  - Reuber M
LA  - eng
PT  - Journal Article
PT  - Review
PT  - Systematic Review
DEP - 20070807
PL  - Switzerland
TA  - Gerontology
JT  - Gerontology
JID - 7601655
RN  - 0 (Anticonvulsants)
SB  - IM
MH  - Aged
MH  - Anticonvulsants/therapeutic use
MH  - Confusion/*etiology
MH  - Diagnosis, Differential
MH  - Electroencephalography
MH  - Humans
MH  - Status Epilepticus/*diagnosis/drug therapy
RF  - 57
EDAT- 2007/08/09 09:00
MHDA- 2008/07/04 09:00
CRDT- 2007/08/09 09:00
PHST- 2007/03/20 00:00 [received]
PHST- 2007/06/05 00:00 [accepted]
PHST- 2007/08/09 09:00 [pubmed]
PHST- 2008/07/04 09:00 [medline]
PHST- 2007/08/09 09:00 [entrez]
AID - 000106829 [pii]
AID - 10.1159/000106829 [doi]
PST - ppublish
SO  - Gerontology. 2007;53(6):388-96. doi: 10.1159/000106829. Epub 2007 Aug 7.