PMID- 1768552
OWN - NLM
STAT- MEDLINE
DCOM- 19920225
LR  - 20190515
IS  - 0007-0912 (Print)
IS  - 0007-0912 (Linking)
VI  - 67
IP  - 6
DP  - 1991 Dec
TI  - Non-invasive measurement of cardiac output by thoracic electrical bioimpedance: a 
      study of reproducibility and comparison with thermodilution.
PG  - 788-94
AB  - The performance and reproducibility of the BoMED NCCOM3 thoracic electrical 
      bioimpedance cardiograph (TEB) has been evaluated in volunteers and patients. In 
      resting supine volunteers, we determined the coefficient of variability over 
      short time periods (30 min) and over several days, and examined the effects of 
      differences in electrode type and electrode placement. The mean (range) 
      intra-subject coefficients of variation (CV) for thoracic fluid index (TFI) and 
      stroke volume (SV) were 1.0% (0.4-1.8%) and 4.7% (2.1-8.5%), respectively over a 
      30-min period. The corresponding CV were 5.6% (2.3-10.9%) and 10.9% (6.1-14.8%) 
      for measurements made at rest on four separate occasions. Use of different 
      electrode types (RedDot and Medicotest) resulted in differences in TFI (P less 
      than 0.01), but not in mean values for SV or cardiac output (Q); their use in 
      individual subjects revealed differences of up to 20% in SV and Q. Alterations in 
      electrode placement by 5 cm in the horizontal and diagonal planes produced no 
      significant changes in TFI, SV or Q; changes in the longitudinal plane produced a 
      graded change. Increases of 5 cm and 10 cm in thoracic length produced mean 
      increases in TFI of 9.8% and 39.8%, respectively, and mean decreases in Q of 8.4% 
      and 16.7% and SV of 7.5% and 15.8%. TEB measurements of Q and SV were compared 
      with thermodilution (TD) in 16 intensive care patients. Mean (SEM) Q by TEB was 
      5.63 (1.10) litre min-1 compared with TD 4.38 (0.72) litre min-1 (P less than 
      0.01).(ABSTRACT TRUNCATED AT 250 WORDS)
FAU - Jewkes, C
AU  - Jewkes C
AD  - Nuffield Department of Anaesthetics, University of Oxford, Radcliffe Infirmary.
FAU - Sear, J W
AU  - Sear JW
FAU - Verhoeff, F
AU  - Verhoeff F
FAU - Sanders, D J
AU  - Sanders DJ
FAU - Foex, P
AU  - Foex P
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - England
TA  - Br J Anaesth
JT  - British journal of anaesthesia
JID - 0372541
SB  - IM
MH  - Adult
MH  - *Cardiac Output
MH  - *Cardiography, Impedance/instrumentation/methods
MH  - Electrodes
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Reproducibility of Results
MH  - Stroke Volume
MH  - Supine Position
MH  - Thermodilution
EDAT- 1991/12/01 00:00
MHDA- 1991/12/01 00:01
CRDT- 1991/12/01 00:00
PHST- 1991/12/01 00:00 [pubmed]
PHST- 1991/12/01 00:01 [medline]
PHST- 1991/12/01 00:00 [entrez]
AID - S0007-0912(17)47855-X [pii]
AID - 10.1093/bja/67.6.788 [doi]
PST - ppublish
SO  - Br J Anaesth. 1991 Dec;67(6):788-94. doi: 10.1093/bja/67.6.788.