PMID- 17688858
OWN - NLM
STAT- MEDLINE
DCOM- 20070821
LR  - 20181201
IS  - 1579-2242 (Electronic)
IS  - 0300-8932 (Linking)
VI  - 60
IP  - 8
DP  - 2007 Aug
TI  - [Clinical experience with levosimendan in the emergency department of a tertiary 
      care hospital].
PG  - 878-82
AB  - The efficacy and safety of levosimendan administration in patients with acute 
      heart failure admitted to intensive care units has been well established. 
      However, no information is available on the drug's beneficial effects in 
      emergency departments. We studied 40 patients with acute heart failure who showed 
      no or only partial improvement after conventional treatment and who received 
      levosimendan during the period 2005-2006. The patients' mean age was 76 (9) 
      years. The most common etiology was ischemic heart disease, and 85% of patients 
      were in New York Heart Association (NYHA) class III or IV. The clinical response 
      was favorable in 82% of patients, while adverse effects occurred in 18%. Some 70% 
      were admitted to the emergency department short-stay unit. These findings 
      indicate that levosimendan can be used safely and effectively in hospital 
      emergency departments.
FAU - Llorens-Soriano, Pere
AU  - Llorens-Soriano P
AD  - Servicio de Urgencias-UCE-UHD, Hospital General Universitario de Alicante, 
      Alicante, Spain. llorens ped@gva.es
FAU - Carbajosa-Dalmau, Jose
AU  - Carbajosa-Dalmau J
FAU - Fernandez-Canadas, Jose
AU  - Fernandez-Canadas J
FAU - Murcia-Zaragoza, Jose
AU  - Murcia-Zaragoza J
FAU - Climent-Paya, Vicente
AU  - Climent-Paya V
FAU - Laghzaoui, Fadoua
AU  - Laghzaoui F
FAU - Dieguez-Zaragoza, Santiago
AU  - Dieguez-Zaragoza S
FAU - Carrasco-Moreno, Rafael
AU  - Carrasco-Moreno R
LA  - spa
PT  - Clinical Trial
PT  - Journal Article
TT  - Experiencia clinica con levosimendan en un servicio de urgencias de un hospital 
      de tercer nivel.
PL  - Spain
TA  - Rev Esp Cardiol
JT  - Revista espanola de cardiologia
JID - 0404277
RN  - 0 (Cardiotonic Agents)
RN  - 0 (Hydrazones)
RN  - 0 (Pyridazines)
RN  - 349552KRHK (Simendan)
SB  - IM
CIN - Rev Esp Cardiol. 2008 May;61(5):545-6; author reply 546. PMID: 18462660
MH  - Acute Disease
MH  - Aged
MH  - Cardiotonic Agents/*therapeutic use
MH  - Emergency Service, Hospital
MH  - Emergency Treatment
MH  - Female
MH  - Heart Failure/*drug therapy
MH  - Humans
MH  - Hydrazones/*therapeutic use
MH  - Male
MH  - Prospective Studies
MH  - Pyridazines/*therapeutic use
MH  - Simendan
EDAT- 2007/08/11 09:00
MHDA- 2007/08/22 09:00
CRDT- 2007/08/11 09:00
PHST- 2007/08/11 09:00 [pubmed]
PHST- 2007/08/22 09:00 [medline]
PHST- 2007/08/11 09:00 [entrez]
AID - 13109003 [pii]
PST - ppublish
SO  - Rev Esp Cardiol. 2007 Aug;60(8):878-82.