PMID- 17694402
OWN - NLM
STAT- MEDLINE
DCOM- 20071211
LR  - 20220410
IS  - 0932-0113 (Print)
IS  - 0932-0113 (Linking)
VI  - 101
IP  - 6
DP  - 2007 Nov
TI  - Hematological and biochemical changes in organically farmed sheep naturally 
      infected with Fasciola hepatica.
PG  - 1657-61
AB  - A naturally occurring outbreak of fasciolosis in a group of 20 Merinolandschaf 
      (German Merino) sheep was studied. Hematological and blood biochemical values in 
      sheep spontaneously infected with liver fluke Fasciola hepatica were compared 
      with equivalent values in 20 parasite-free sheep from organically farmed flock. 
      Investigated animals were kept in outdoor system, on pastures covered with 
      swamps, which remain flooded after rainy season. Significantly lower red blood 
      cell (RBC) count, lymphocytes, hemoglobin (Hb), packed cell volume (PCV), mean 
      corpuscular hemoglobin concentration (MCHC), aspartate aminotransferase (AST), 
      blood urea nitrogen (BUN), creatinine, and albumin were recorded in sheep from 
      the infected herd, whereas white blood cell (WBC) count, eosinophil, segmented 
      and band neutrophil count, mean corpuscular volume (MCV), gamma-glutamyl 
      transferase (GGT), concentrations of glucose, and globulins were significantly 
      higher than in the parasite free herd. No significant correlation between the 
      investigated blood parameters and the number of F. hepatica eggs in the feces was 
      detected. This study shows that hematological and biochemical values can be 
      useful in early diagnosis and prognosis of sheep fasciolosis.
FAU - Matanovic, K
AU  - Matanovic K
AD  - Department of Physiology and Radiobiology, Faculty of Veterinary Medicine, 
      University of Zagreb, Heinzelova 55, 10000 Zagreb, Croatia. kmatanov@vef.hr
FAU - Severin, K
AU  - Severin K
FAU - Martinkovic, F
AU  - Martinkovic F
FAU - Simpraga, M
AU  - Simpraga M
FAU - Janicki, Z
AU  - Janicki Z
FAU - Barisic, J
AU  - Barisic J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20070813
PL  - Germany
TA  - Parasitol Res
JT  - Parasitology research
JID - 8703571
RN  - 0 (Blood Proteins)
SB  - IM
MH  - Agriculture/*methods
MH  - Animals
MH  - Blood Proteins/analysis
MH  - Fasciola hepatica/*pathogenicity
MH  - Fascioliasis/diagnosis/epidemiology/parasitology/*veterinary
MH  - Feces/parasitology
MH  - Hematologic Tests
MH  - Parasite Egg Count
MH  - Severity of Illness Index
MH  - *Sheep
MH  - Sheep Diseases/diagnosis/epidemiology/parasitology/*physiopathology
EDAT- 2007/08/19 09:00
MHDA- 2007/12/12 09:00
CRDT- 2007/08/19 09:00
PHST- 2007/07/10 00:00 [received]
PHST- 2007/07/30 00:00 [accepted]
PHST- 2007/08/19 09:00 [pubmed]
PHST- 2007/12/12 09:00 [medline]
PHST- 2007/08/19 09:00 [entrez]
AID - 10.1007/s00436-007-0709-2 [doi]
PST - ppublish
SO  - Parasitol Res. 2007 Nov;101(6):1657-61. doi: 10.1007/s00436-007-0709-2. Epub 2007 
      Aug 13.