PMID- 17706035 OWN - NLM STAT- MEDLINE DCOM- 20071030 LR - 20151119 IS - 1008-8830 (Print) IS - 1008-8830 (Linking) VI - 9 IP - 4 DP - 2007 Aug TI - [Juvenile psoriatic arthritis]. PG - 339-42 AB - A case of juvenile psoriatic arthritis in a 12 year-old boy was reported. The patient had a history of one and half a year of bilateral heel pain, followed by pain in the right knee and ankle and right hip joint. He developed psoriatic lesions affecting his nails and skin. He had increased erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) contents. Human leukocyte antigen (HLA) B27 was detected but serum rheumatoid factor was not in the patient. A skin biopsy revealed psoriasis and ultrasonography demonstrated synovitis in right knee and ankle. Juvenile psoriatic arthritis was diagnosed based on his physical, laboratory and skin biopsy findings. A treatment with nonsteroidal anti-inflammatory drugs and sulfasalazine produced no effect. Leflunomide in conjunction with anti-TNF biologic agents (Etanercept) was administered, followed by symptomatic improvement 2 weeks later. FAU - Lu, Shan AU - Lu S AD - Department of Pediatrics, Peking University Third Hospital, Beijing 100083, China. lucm@ccps.gov.cn FAU - Zhou, Wei AU - Zhou W FAU - Zhang, Qian AU - Zhang Q FAU - Yu, Xin-Ying AU - Yu XY FAU - Liu, Dong-Ming AU - Liu DM FAU - Liu, Xiang-Yuan AU - Liu XY LA - chi PT - Case Reports PT - English Abstract PT - Journal Article PL - China TA - Zhongguo Dang Dai Er Ke Za Zhi JT - Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics JID - 100909956 RN - 0 (Immunoglobulin G) RN - 0 (Receptors, Tumor Necrosis Factor) RN - 0 (Tumor Necrosis Factor-alpha) RN - OP401G7OJC (Etanercept) SB - IM MH - Arthritis, Psoriatic/diagnosis/*drug therapy/etiology MH - Child MH - Diagnosis, Differential MH - Etanercept MH - Humans MH - Immunoglobulin G/therapeutic use MH - Male MH - Receptors, Tumor Necrosis Factor/therapeutic use MH - Tumor Necrosis Factor-alpha/antagonists & inhibitors EDAT- 2007/08/21 09:00 MHDA- 2007/10/31 09:00 CRDT- 2007/08/21 09:00 PHST- 2007/08/21 09:00 [pubmed] PHST- 2007/10/31 09:00 [medline] PHST- 2007/08/21 09:00 [entrez] AID - 1008-8830(2007)04-0339-04 [pii] PST - ppublish SO - Zhongguo Dang Dai Er Ke Za Zhi. 2007 Aug;9(4):339-42.