PMID- 17713720
OWN - NLM
STAT- MEDLINE
DCOM- 20080226
LR  - 20220716
IS  - 0167-594X (Print)
IS  - 0167-594X (Linking)
VI  - 86
IP  - 2
DP  - 2008 Jan
TI  - A supratentorial primitive neuroectodermal tumor in an adult: a case report and 
      review of the literature.
PG  - 217-24
AB  - Supratentorial primitive neuroectodermal tumors (sPNET) occurring in adults are 
      rare. Only 56 such cases have been previously reported. This report documents a 
      56-year-old male who presented with the chief complaint of right facial palsy. 
      Magnetic resonance imaging (MRI) revealed left frontal and bilateral 
      periventricular lesions. Surgery was performed for the frontal mass, which was 
      histologically diagnosed to be sPNET. An immunohistochemistry assay for CD99, and 
      a fluorescence in situ hybridization (FISH) assay for t(11;22) translocation 
      revealed this PNET to be a central PNET. This case was the first case to detect a 
      central PNET using both immunohistochemistry and the FISH assay in adult sPNET. 
      Though radiation therapy was performed, an MRI performed 2.5 months after the 
      surgery revealed a regrowth of the tumor. The patient died 5 months after 
      surgery. This case report is accompanied by a review of 57 cases of adult sPNET.
FAU - Ohba, Shigeo
AU  - Ohba S
AD  - Department of Neurosurgery, Keio University School of Medicine, 35 Shinano-machi, 
      Shinjuku-ku, Tokyo, Japan. shigeo.ohba@gmail.com
FAU - Yoshida, Kazunari
AU  - Yoshida K
FAU - Hirose, Yuichi
AU  - Hirose Y
FAU - Ikeda, Eiji
AU  - Ikeda E
FAU - Kawase, Takeshi
AU  - Kawase T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PT  - Review
DEP - 20070823
PL  - United States
TA  - J Neurooncol
JT  - Journal of neuro-oncology
JID - 8309335
RN  - 0 (12E7 Antigen)
RN  - 0 (Antigens, CD)
RN  - 0 (CD99 protein, human)
RN  - 0 (Cell Adhesion Molecules)
SB  - IM
MH  - 12E7 Antigen
MH  - Antigens, CD/metabolism
MH  - Cell Adhesion Molecules/metabolism
MH  - Fatal Outcome
MH  - Humans
MH  - Immunochemistry
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Middle Aged
MH  - Neuroectodermal Tumors, 
      Primitive/genetics/metabolism/*pathology/radiotherapy/surgery
MH  - Supratentorial Neoplasms/genetics/metabolism/*pathology/radiotherapy/surgery
MH  - Translocation, Genetic
RF  - 32
EDAT- 2007/08/24 09:00
MHDA- 2008/02/27 09:00
CRDT- 2007/08/24 09:00
PHST- 2007/03/26 00:00 [received]
PHST- 2007/08/07 00:00 [accepted]
PHST- 2007/08/24 09:00 [pubmed]
PHST- 2008/02/27 09:00 [medline]
PHST- 2007/08/24 09:00 [entrez]
AID - 10.1007/s11060-007-9466-4 [doi]
PST - ppublish
SO  - J Neurooncol. 2008 Jan;86(2):217-24. doi: 10.1007/s11060-007-9466-4. Epub 2007 
      Aug 23.