PMID- 17718924
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20110714
LR  - 20181113
IS  - 1752-1947 (Print)
IS  - 1752-1947 (Electronic)
IS  - 1752-1947 (Linking)
VI  - 1
DP  - 2007 Aug 25
TI  - Proton pump inhibitor-responsive chronic cough without acid reflux: a case 
      report.
PG  - 69
AB  - BACKGROUND: Because 24-h esophageal pH monitoring is quite invasive, the 
      diagnosis of gastroesophageal reflux disease (GERD)-associated cough has usually 
      been made based merely on the clinical efficacy of treatment with proton pump 
      inhibitor (PPI). CASE PRESENTATION: We recently encountered two patients with 
      PPI-responsive chronic non-productive cough for whom switching from 
      bronchodilators and glucocorticosteroids to PPI resulted in improvement of cough. 
      The cough returned nearly to pre-administration level a few weeks after 
      discontinuation of PPI. Though GERD-associated cough was suspected, 24-h 
      esophageal pH monitoring revealed that the cough rarely involved gastric acid 
      reflux. Following re-initiation of PPI, the cough disappeared again. CONCLUSION: 
      PPI may improve cough unrelated to gastric acid reflux.
FAU - Nobata, Kouichi
AU  - Nobata K
AD  - The Department of Internal Medicine, Imizu City Hospital, Imizu, JapanAbstract. 
      k-nobata@yg7.so-net.ne.jp.
FAU - Asanoi, Hidetsugu
AU  - Asanoi H
LA  - eng
PT  - Journal Article
DEP - 20070825
PL  - England
TA  - J Med Case Rep
JT  - Journal of medical case reports
JID - 101293382
PMC - PMC2008204
EDAT- 2007/08/28 09:00
MHDA- 2007/08/28 09:01
PMCR- 2007/08/25
CRDT- 2007/08/28 09:00
PHST- 2007/04/09 00:00 [received]
PHST- 2007/08/25 00:00 [accepted]
PHST- 2007/08/28 09:00 [pubmed]
PHST- 2007/08/28 09:01 [medline]
PHST- 2007/08/28 09:00 [entrez]
PHST- 2007/08/25 00:00 [pmc-release]
AID - 1752-1947-1-69 [pii]
AID - 10.1186/1752-1947-1-69 [doi]
PST - epublish
SO  - J Med Case Rep. 2007 Aug 25;1:69. doi: 10.1186/1752-1947-1-69.