PMID- 1776316
OWN - NLM
STAT- MEDLINE
DCOM- 19920305
LR  - 20061115
IS  - 0300-967X (Print)
IS  - 0300-967X (Linking)
VI  - 195
IP  - 6
DP  - 1991 Nov-Dec
TI  - [Analysis of neonatal and fetal blood for the diagnosis of congenital 
      toxoplasmosis infection].
PG  - 262-6
AB  - A total of 175 serum samples, including 35 obtained from neonates and 5 from 
      fetuses in whom connatal toxoplasma infection was suspected, were simultaneously 
      tested for toxoplasma-specific IgA and IgM antibodies by immunosorbent 
      agglutination assay (ISAGA). If sufficient serum was available, IgM-IIFT 
      (Remington test) was also performed prior to and following IgG absorption. All 
      the control samples from children not infected with toxoplasma (SFT negative, or 
      titers less than or equal to 1:256) were negative in the IgA and IgM ISAGA. Of 
      the 35 congenitally infected children, results were positive in 91.4% in the IgA 
      and/or the IgM ISAGA. Of 5 fetuses with positive results in animal experiments 3 
      were positive in the IgM ISAGA. The serum from the fourth fetus was low positive 
      in the IgM IIFT, while that from the fifth fetus was both IgM- and IgA-negative. 
      The results of this study show that several methods should always be used 
      simultaneously to detect connatal toxoplasma infection.
FAU - Saathoff, M
AU  - Saathoff M
AD  - Institut fur Medizinische Parasitologie, Universitat Bonn.
FAU - Seitz, H M
AU  - Seitz HM
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Untersuchung von Neugeborenen- und Fetalseren zur Erfassung von konnatalen 
      Toxoplasma-Infektionen.
PL  - Germany
TA  - Z Geburtshilfe Perinatol
JT  - Zeitschrift fur Geburtshilfe und Perinatologie
JID - 0326205
RN  - 0 (Antibodies, Protozoan)
RN  - 0 (Immunoglobulin A)
RN  - 0 (Immunoglobulin M)
SB  - IM
MH  - Antibodies, Protozoan/*isolation & purification
MH  - Fetal Blood/*immunology
MH  - Fluorescent Antibody Technique
MH  - Humans
MH  - Immunoglobulin A/isolation & purification
MH  - Immunoglobulin M/isolation & purification
MH  - Immunosorbent Techniques
MH  - Infant, Newborn
MH  - Toxoplasmosis, Congenital/*immunology
EDAT- 1991/11/01 00:00
MHDA- 1991/11/01 00:01
CRDT- 1991/11/01 00:00
PHST- 1991/11/01 00:00 [pubmed]
PHST- 1991/11/01 00:01 [medline]
PHST- 1991/11/01 00:00 [entrez]
PST - ppublish
SO  - Z Geburtshilfe Perinatol. 1991 Nov-Dec;195(6):262-6.