PMID- 17786888
OWN - NLM
STAT- MEDLINE
DCOM- 20071130
LR  - 20070905
IS  - 0303-4259 (Print)
IS  - 0303-4259 (Linking)
VI  - 34 Suppl 3
DP  - 2007 Sep
TI  - [Physical training in the treatment of depressive disorders].
PG  - S300-4
AB  - Therapeutic exercise programs have become an obligatory component in the modern 
      treatment of many internal and orthopaedic conditions. In the field of 
      psychiatry, the interaction of physical fitness and mental well-being has been 
      increasingly recognized. In the meanwhile, solid evidence has emerged that 
      regular exercise is associated with therapeutic effects in psychiatric patients 
      suffering from depressive and possibly other psychiatric disorders. The present 
      article reviews the relevant literature and summarizes neurobiological effects of 
      exercise which might play a role in the effectiveness of therapeutic exercise. 
      For instance, there is experimental evidence, that regular exercise induces a 
      downregulation of central 5-HT(2C) receptors which play an important role in the 
      pathogenesis of anxiety and depression. The production of brain-derived 
      neurotrophic factor (BDNF)is stimulated in several brain regions. In conclusion, 
      practical aspects and motivational factors have to be regarded in order to 
      successfully establish exercise programs in the treatment of psychiatric 
      disorders.
FAU - Broocks, Andreas
AU  - Broocks A
AD  - Carl-Friedrich-Flemming-Klinik, HELIOS-Kliniken Schwerin, Wismarsche Strasse 
      393-397, 19055 Schwerin. abroocks@schwerin.helios-kliniken.de
FAU - Ahrendt, Uwe
AU  - Ahrendt U
FAU - Sommer, Marcel
AU  - Sommer M
LA  - ger
PT  - English Abstract
PT  - Journal Article
TT  - Korperliches Training in der Behandlung depressiver Erkrankungen.
PL  - Germany
TA  - Psychiatr Prax
JT  - Psychiatrische Praxis
JID - 0423204
RN  - 0 (Antidepressive Agents)
SB  - IM
MH  - Antidepressive Agents/therapeutic use
MH  - Combined Modality Therapy
MH  - Depressive Disorder/psychology/*therapy
MH  - Evidence-Based Medicine
MH  - *Exercise
MH  - Humans
MH  - Physical Endurance
MH  - Treatment Outcome
MH  - Weight Lifting
EDAT- 2007/10/27 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/10/27 09:00
PHST- 2007/10/27 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/10/27 09:00 [entrez]
AID - 10.1055/s-2007-970948 [doi]
PST - ppublish
SO  - Psychiatr Prax. 2007 Sep;34 Suppl 3:S300-4. doi: 10.1055/s-2007-970948.