PMID- 17805954 OWN - NLM STAT- MEDLINE DCOM- 20080205 LR - 20220331 IS - 0920-3206 (Print) IS - 0920-3206 (Linking) VI - 21 IP - 5 DP - 2007 Oct TI - Determinants of costs and the length of stay in acute coronary syndromes: a real life analysis of more than 10,000 patients. PG - 389-98 AB - AIMS: The aim of this study was to investigate inpatient costs of acute coronary syndromes (ACS) in Switzerland and to assess the main cost drivers associated with this disease. METHODS AND RESULTS: We used the national multicenter registry AMIS (acute myocardial infarction in Switzerland) which includes a representative number of 65 hospitals and a total of 11.623 patient records. The following cost modules were analyzed: hospital stay, percutaneous coronary interventions (PCI) and thrombolysis. Expenses were assessed using data from official Swiss national statistical sources. Mean total costs per patient were 12.101 Euro (median 10.929 Euro; 95% CI: 1.161-27.722 Euro). The length of stay ranged from one to 129 days with a mean of 9.5 days (median 8.0 days; 95% CI: 1-23). Overall costs were independently influenced by age, gender and existent co-morbidities, e.g. cerebrovascular disease and diabetes (p < 0.0001). CONCLUSION: Our study determined specific causes for the high costs associated with hospital treatment on a large representative sample. The results should highlight unnecessary expenses and help policy makers to evaluate the base case for a DRG (Diagnosis Related Groups) scenario in Switzerland. Cost weighting of the identified secondary diagnosis should be considered in the calculation and coding of a primary diagnosis for ACS. FAU - Bramkamp, Matthias AU - Bramkamp M AD - Department of Internal Medicine, University Hospital of Zurich, RAE B 40, Ramistr. 100, CH-8091 Zurich, Switzerland. Matthias.Bramkamp@usz.ch FAU - Radovanovic, Dragana AU - Radovanovic D FAU - Erne, Paul AU - Erne P FAU - Szucs, Thomas D AU - Szucs TD LA - eng PT - Journal Article PL - United States TA - Cardiovasc Drugs Ther JT - Cardiovascular drugs and therapy JID - 8712220 SB - IM MH - Acute Coronary Syndrome/diagnosis/*economics/therapy MH - Aged MH - Angioplasty, Balloon, Coronary/*economics/statistics & numerical data MH - Comorbidity MH - Databases, Factual/statistics & numerical data MH - Female MH - Hospital Costs/*statistics & numerical data MH - Humans MH - Length of Stay/*economics/statistics & numerical data MH - Male MH - Middle Aged MH - Multivariate Analysis MH - *Outcome Assessment, Health Care MH - *Registries MH - Risk Factors MH - Switzerland MH - Thrombolytic Therapy/*economics/statistics & numerical data EDAT- 2007/09/07 09:00 MHDA- 2008/02/06 09:00 CRDT- 2007/09/07 09:00 PHST- 2007/09/07 09:00 [pubmed] PHST- 2008/02/06 09:00 [medline] PHST- 2007/09/07 09:00 [entrez] AID - 10.1007/s10557-007-6044-0 [doi] PST - ppublish SO - Cardiovasc Drugs Ther. 2007 Oct;21(5):389-98. doi: 10.1007/s10557-007-6044-0.