PMID- 17821976
OWN - NLM
STAT- MEDLINE
DCOM- 20160423
LR  - 20181201
IS  - 0094-2405 (Print)
IS  - 0094-2405 (Linking)
VI  - 34
IP  - 7
DP  - 2007 Jul
TI  - Multichannel detectors for profile measurements in clinical proton fields.
PG  - 2683-90
AB  - Two beam profile measurement detectors have been developed at Indiana University 
      Cyclotron Facility to address the need for a tool to efficiently verify dose 
      distributions created with active methods of clinical proton beam delivery. The 
      multipad ionization chamber (MPIC) has 128 ionization chambers arranged in one 
      plane and is designed to measure lateral profiles in fields up to 38 cm in 
      diameter. The MPIC pads have a 5 mm pitch for fields up to 20 cm in diameter and 
      a 7 mm pitch for larger fields, providing the accuracy of field size 
      determination about 0.5 mm. The multilayer ionization chamber (MLIC) detector 
      contains 122 small-volume ionization chambers stacked at a 1.82 mm step 
      (water-equivalent) for depth-dose profile measurements. The MLIC detector can 
      measure profiles up to 20 cm in depth, and determine the 80% distal dose fall-off 
      with about 0.1 mm precision. Both detectors can be connected to the same set of 
      electronics modules, which comprise the detectors' data acquisition system. The 
      detectors have been tested in clinical proton fields produced with active methods 
      of beam delivery such as uniform scanning and energy stacking. This article 
      describes detector performance tests and discusses their results. The test 
      results indicate that the MPIC and MLIC detectors can be used for dosimetric 
      characterization of clinical proton fields. The detectors offer significant time 
      savings during measurements in actively delivered beams compared with traditional 
      measurements using a water phantom.
FAU - Nichiporov, Dmitri
AU  - Nichiporov D
AD  - Indiana University Cyclotron Facility, 2401 Milo B. Sampson Lane, Bloomington, 
      Indiana 47408, USA. nichipor@indiana.edu
FAU - Solberg, Keith
AU  - Solberg K
FAU - Hsi, Wen
AU  - Hsi W
FAU - Wolanski, Mark
AU  - Wolanski M
FAU - Mascia, Anthony
AU  - Mascia A
FAU - Farr, Jonathan
AU  - Farr J
FAU - Schreuder, Andries
AU  - Schreuder A
LA  - eng
GR  - C06 RR17407-01/RR/NCRR NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - Med Phys
JT  - Medical physics
JID - 0425746
RN  - 0 (Protons)
RN  - 059QF0KO0R (Water)
SB  - IM
MH  - Humans
MH  - Phantoms, Imaging
MH  - *Protons
MH  - *Radiometry
MH  - Water
EDAT- 2007/09/08 09:00
MHDA- 2016/04/24 06:00
CRDT- 2007/09/08 09:00
PHST- 2007/09/08 09:00 [pubmed]
PHST- 2016/04/24 06:00 [medline]
PHST- 2007/09/08 09:00 [entrez]
AID - 10.1118/1.2746513 [doi]
PST - ppublish
SO  - Med Phys. 2007 Jul;34(7):2683-90. doi: 10.1118/1.2746513.