PMID- 17827678 OWN - NLM STAT- MEDLINE DCOM- 20071212 LR - 20070926 IS - 0916-8451 (Print) IS - 0916-8451 (Linking) VI - 71 IP - 9 DP - 2007 Sep TI - Characterization of antibacterial nanoparticles from the scallop, Ptinopecten yessoensis. PG - 2242-7 AB - To develop a new drug delivery system, antibacterial 50-900 nm nanoparticles of shell and internal organs from scallops collected off Huksan-Island, Korea, were prepared by dry grind technology respectively. The diameters, identities, and conformations of the scallop shell and internal organ particles were determined with a particle-size analyzer and by X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and Raman spectroscopy. The antibacterial properties of the nanoparticles from scallop shell were investigated in the absence and the presence of scallop-shell extract. Bacterial growth was reduced with the supernatant of the nanoparticle scallop-shell extract. Also, the nanoparticles from scallop shell were much more effective as a skin softener than was powder. These facts provide us with guidelines for the study of the size-dependent properties of functional materials as well as for further applications to drug delivery systems (DDSs) and cosmetic raw materials. FAU - Jeong, Mi Suk AU - Jeong MS AD - Research Center for Advanced Science and Technology, Dongseo University, Busan 617-716, Korea. FAU - Park, Jeong Soon AU - Park JS FAU - Song, Seong Hwan AU - Song SH FAU - Jang, Se Bok AU - Jang SB LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20070907 PL - England TA - Biosci Biotechnol Biochem JT - Bioscience, biotechnology, and biochemistry JID - 9205717 RN - 0 (Anti-Bacterial Agents) SB - IM MH - Animals MH - Anti-Bacterial Agents/*chemistry/*toxicity MH - Microbial Viability/drug effects MH - Microscopy, Electron, Scanning MH - Nanoparticles/*chemistry/*ultrastructure MH - Particle Size MH - Pectinidae/*chemistry MH - Staphylococcus epidermidis/drug effects MH - X-Ray Diffraction EDAT- 2007/09/11 09:00 MHDA- 2007/12/13 09:00 CRDT- 2007/09/11 09:00 PHST- 2007/09/11 09:00 [pubmed] PHST- 2007/12/13 09:00 [medline] PHST- 2007/09/11 09:00 [entrez] AID - JST.JSTAGE/bbb/70228 [pii] AID - 10.1271/bbb.70228 [doi] PST - ppublish SO - Biosci Biotechnol Biochem. 2007 Sep;71(9):2242-7. doi: 10.1271/bbb.70228. Epub 2007 Sep 7.