PMID- 17867800
OWN - NLM
STAT- MEDLINE
DCOM- 20071126
LR  - 20220309
IS  - 1083-3668 (Print)
IS  - 1083-3668 (Linking)
VI  - 12
IP  - 4
DP  - 2007 Jul-Aug
TI  - Three-dimensional optical coherence tomography at 1050 nm versus 800 nm in 
      retinal pathologies: enhanced performance and choroidal penetration in cataract 
      patients.
PG  - 041211
AB  - Frequency domain optical coherence tomography (FD-OCT), based on an 
      all-reflective high-speed InGaAs spectrometer, operating in the 1050 nm 
      wavelength region for retinal diagnostics, enables high-speed, volumetric imaging 
      of retinal pathologies with greater penetration into choroidal tissue is compared 
      to conventional 800 nm three-dimensional (3-D) ophthalmic FD-OCT systems. 
      Furthermore, the lower scattering at this wavelength significantly improves 
      imaging performance in cataract patients, thereby widening the clinical 
      applicability of ophthalmic OCT. The clinical performance of two 
      spectrometer-based ophthalmic 3-D OCT systems compared in respect to their 
      clinical performance, one operating at 800 nm with 150 nm bandwidth 
      (approximately 3 microm effective axial resolution) and the other at 1050 nm with 
      70 nm bandwidth (approximately 7 microm effective axial resolution). Results 
      achieved with 3-D OCT at 1050 nm reveal, for the first time, decisive 
      improvements in image quality for patients with retinal pathologies and 
      clinically significant cataract.
FAU - Povazay, Boris
AU  - Povazay B
AD  - Cardiff University, School of Optometry and Vision Sciences, Biomedical Imaging 
      Group, Cardiff, Wales, CF24 4LU, United Kingdom.
FAU - Hermann, Boris
AU  - Hermann B
FAU - Unterhuber, Angelika
AU  - Unterhuber A
FAU - Hofer, Bernd
AU  - Hofer B
FAU - Sattmann, Harald
AU  - Sattmann H
FAU - Zeiler, Florian
AU  - Zeiler F
FAU - Morgan, James E
AU  - Morgan JE
FAU - Falkner-Radler, Christiane
AU  - Falkner-Radler C
FAU - Glittenberg, Carl
AU  - Glittenberg C
FAU - Blinder, Susanne
AU  - Blinder S
FAU - Drexler, Wolfgang
AU  - Drexler W
LA  - eng
PT  - Comparative Study
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - J Biomed Opt
JT  - Journal of biomedical optics
JID - 9605853
SB  - IM
MH  - Algorithms
MH  - Cataract/*pathology
MH  - Choroid/*pathology
MH  - Humans
MH  - Image Enhancement/*methods
MH  - Image Interpretation, Computer-Assisted/methods
MH  - Imaging, Three-Dimensional/*methods
MH  - Reproducibility of Results
MH  - Retina/pathology
MH  - Retinal Diseases/*pathology
MH  - Retinoscopy/*methods
MH  - Sensitivity and Specificity
MH  - Spectrophotometry, Infrared/methods
MH  - Tomography, Optical Coherence/*methods
EDAT- 2007/09/18 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/09/18 09:00
PHST- 2007/09/18 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/09/18 09:00 [entrez]
AID - 10.1117/1.2773728 [doi]
PST - ppublish
SO  - J Biomed Opt. 2007 Jul-Aug;12(4):041211. doi: 10.1117/1.2773728.