PMID- 17869045 OWN - NLM STAT- MEDLINE DCOM- 20080430 LR - 20161124 IS - 0385-8146 (Print) IS - 0385-8146 (Linking) VI - 35 IP - 1 DP - 2008 Mar TI - Influence of visual information and test paradigm on clinical olfactory test results. PG - 53-60 AB - OBJECTIVE: The goal of this study was to determine if visual information and test paradigms affect clinical olfactory test results. METHODS: Three hundred and ninety-seven Japanese patients with complaints of olfactory dysfunction were administered both a new clinical olfactory test, the Odor Stick Identification Test for Japanese (OSIT-J), and the Japanese benchmark olfactory test, T&T olfactometry. Four different methods were used to administer the OSIT-J combining paradigms using word or picture-word alternatives with the four-plus alternative method based on a top-down strategy or the two-step identification method based on a bottom-up strategy. OSIT-J scores were compared for the different methods, referring to benchmark scores obtained with T&T olfactometry. RESULTS: OSIT-J scores using picture-word alternatives and the four-plus alternative method showed a stronger correlation with T&T olfactometry test scores than those using word alternatives and the two-step identification method, respectively. The average OSIT-J scores of the four-plus alternative method using picture-word alternatives were significantly higher than those using word alternatives in anosmic and severely hyposmic patients. The time required to administer the OSIT-J using both picture-word alternatives and the four-plus alternative method was the shortest of the four OSIT-J methods. CONCLUSIONS: Visual information and test paradigms may affect clinical olfactory test results. The OSIT-J method using picture-word alternatives and the four-plus alternative method may be the most suitable for clinical practice. FAU - Kobayashi, Masayoshi AU - Kobayashi M AD - Department of Otorhinolaryngology-Head and Neck Surgery, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, Mie 514-8507, Japan. m-koba@doc.medic.mie-u.ac.jp FAU - Imanishi, Yoshinori AU - Imanishi Y FAU - Ishikawa, Masako AU - Ishikawa M FAU - Nishida, Kohei AU - Nishida K FAU - Oishi, Maaya AU - Oishi M FAU - Nakamura, Satoshi AU - Nakamura S FAU - Sakaida, Hiroshi AU - Sakaida H FAU - Maeda, Taro AU - Maeda T FAU - Tsunoda, Takatsugu AU - Tsunoda T FAU - Matsuura, Toru AU - Matsuura T FAU - Majima, Yuichi AU - Majima Y LA - eng PT - Comparative Study PT - Journal Article DEP - 20070914 PL - Netherlands TA - Auris Nasus Larynx JT - Auris, nasus, larynx JID - 7708170 SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Association Learning MH - Attention MH - Benchmarking MH - Child MH - Female MH - Humans MH - Japan MH - Male MH - Middle Aged MH - *Odorants MH - Olfaction Disorders/*diagnosis MH - *Pattern Recognition, Visual MH - Predictive Value of Tests MH - *Semantics EDAT- 2007/09/18 09:00 MHDA- 2008/05/01 09:00 CRDT- 2007/09/18 09:00 PHST- 2007/01/13 00:00 [received] PHST- 2007/03/28 00:00 [revised] PHST- 2007/04/04 00:00 [accepted] PHST- 2007/09/18 09:00 [pubmed] PHST- 2008/05/01 09:00 [medline] PHST- 2007/09/18 09:00 [entrez] AID - S0385-8146(07)00124-1 [pii] AID - 10.1016/j.anl.2007.04.014 [doi] PST - ppublish SO - Auris Nasus Larynx. 2008 Mar;35(1):53-60. doi: 10.1016/j.anl.2007.04.014. Epub 2007 Sep 14.