PMID- 17874018 OWN - NLM STAT- MEDLINE DCOM- 20080401 LR - 20190606 IS - 1678-4170 (Electronic) IS - 0066-782X (Linking) VI - 89 IP - 2 DP - 2007 Aug TI - Hospital risk factors for bovine pericardial bioprosthesis valve implantation. PG - 113-8, 125-30 AB - BACKGROUND: Identification of preoperative heart valve surgery risk factors aim to improve surgical outcomes with the possibility to offset conditions related to increased morbidity and mortality. OBJECTIVE: Intent of this study is to identify hospital risk factors in patients undergoing bovine pericardial bioprosthesis implantation. METHODS: Retrospective study including 703 consecutive patients who underwent implantation of at least one St. Jude Medical-Biocor bovine pericardial bioprosthesis between September 1991 and December 2005 at the Rio Grande do Sul Cardiology Institute; 392 were aortic, 250 were mitral and 61 were mitroaortic. Characteristics analyzed were gender, age, body mass index, NYHA (New York Heart Association) functional class, ejection fraction, valve lesions, systemic hypertension, diabetes mellitus, kidney function, arrhythmias, prior heart surgery, coronary artery bypass graft, tricuspid valve surgery and elective, urgent or emergency surgery. Main outcome was in-hospital mortality. Relationship between risk factors and in-hospital mortality was analyzed using logistic regression. RESULTS: Were 101 (14.3%) in-hospital deaths. Characteristics with significant relationship to increased mortality were female gender (p<0.001), age over 70 years (p=0.004), atrial fibrillation (p=0.006), diabetes mellitus (p=0.043), creatinine > 2.4 mg/dl (p=0.004), functional class IV (p<0.001), mitral valve lesion (p<0.001), previous heart surgery (p=0.005), tricuspid valve surgery (p<0.001) and emergency surgery (p<0.001). CONCLUSION: Mortality rate observed is accepted by literature and is justifiable due to the high prevalence of risk factors, showing an increased significance level for female gender, age above 70, functional class IV, tricuspid valve repairs and emergency surgery. Offsetting these factors could contribute to reduced in-hospital mortality for valve surgery. FAU - De Bacco, Mateus W AU - De Bacco MW AD - Instituto de Cardiologia do Rio Grande do Sul, Fundacao Universitaria de Cardiologia, Porto Alegre, RS, Brasil. FAU - Sant'Anna, Joao Ricardo M AU - Sant'Anna JR FAU - De Bacco, Gustavo AU - De Bacco G FAU - Sant'Anna, Roberto T AU - Sant'Anna RT FAU - Santos, Marisa F AU - Santos MF FAU - Pereira, Edemar AU - Pereira E FAU - Costa, Altamiro Reis da AU - Costa AR FAU - Prates, Paulo Roberto AU - Prates PR FAU - Kalil, Renato A K AU - Kalil RA FAU - Nesralla, Ivo A AU - Nesralla IA LA - eng LA - por PT - Journal Article PL - Brazil TA - Arq Bras Cardiol JT - Arquivos brasileiros de cardiologia JID - 0421031 SB - IM MH - Adolescent MH - Adult MH - Age Factors MH - Aged MH - Aged, 80 and over MH - Animals MH - Atrial Fibrillation/complications MH - *Bioprosthesis MH - Cattle MH - Diabetes Complications MH - Emergency Treatment/adverse effects MH - Epidemiologic Methods MH - Female MH - Heart Valve Prosthesis Implantation/adverse effects/*mortality MH - Heart Valves/surgery MH - *Hospital Mortality MH - Humans MH - Male MH - Middle Aged MH - Sex Factors EDAT- 2007/09/18 09:00 MHDA- 2008/04/02 09:00 CRDT- 2007/09/18 09:00 PHST- 2006/12/18 00:00 [received] PHST- 2007/03/13 00:00 [accepted] PHST- 2007/09/18 09:00 [pubmed] PHST- 2008/04/02 09:00 [medline] PHST- 2007/09/18 09:00 [entrez] AID - S0066-782X2007001400009 [pii] AID - 10.1590/s0066-782x2007001400009 [doi] PST - ppublish SO - Arq Bras Cardiol. 2007 Aug;89(2):113-8, 125-30. doi: 10.1590/s0066-782x2007001400009.