PMID- 17876271
OWN - NLM
STAT- MEDLINE
DCOM- 20071017
LR  - 20220310
IS  - 0041-1337 (Print)
IS  - 0041-1337 (Linking)
VI  - 84
IP  - 5
DP  - 2007 Sep 15
TI  - Heart valve operations in solid organ recipients: an 18-year single-center 
      experience.
PG  - 592-7
AB  - BACKGROUND: We retrospectively analyzed the outcome of heart valve operations in 
      solid organ recipients, who were referred for operation to our institution. 
      METHODS: Over an 18-year period, 23 heart (group 1) and 16 renal (group 2) 
      transplant recipients in New York Heart Association (NYHA) classes III and IV 
      underwent valve operation. The mean interval from the time of transplantation to 
      cardiac surgery was 77.9 months with a mean follow-up time of 34.6 months in 
      group 1 and 87.2 months with a mean follow-up time of 39.2 months in group 2. 
      RESULTS: Group 1 underwent tricuspid valve replacement (n=12), tricuspid valve 
      reconstruction (n=7), aortic valve replacement (AVR, n=3), and mitral valve 
      replacement (MVR, n=1). In group 2, mechanical valve replacement was performed in 
      14 patients (9 AVR, 3 MVR, 2 AVR and MVR) and tricuspid or mitral valve 
      reconstruction in two patients. There was no operative death. During 
      hospitalization, multiorgan failure due to sepsis was the main cause of mortality 
      (2 in both groups). In the mean follow-up period of 41.2 months, there were four 
      late non-cardiac-related deaths in group 1. Currently 29 surviving transplant 
      recipients (16 heart, 69.6% and 13 renal, 81.3%) are in NYHA classes I and II. 
      CONCLUSION: In heart and renal recipients, valve operations can be performed 
      effectively and safely with acceptable mortality, low cardiac morbidity, and 
      excellent clinical results, although infection is the most serious complication.
FAU - Musci, Michele
AU  - Musci M
AD  - Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, 
      Berlin, Germany. musci@dhzb.de
FAU - Yankah, Charles A
AU  - Yankah CA
FAU - Klose, Holger
AU  - Klose H
FAU - Baretti, Rufus
AU  - Baretti R
FAU - Weng, Yuguo
AU  - Weng Y
FAU - Meyer, Rudolf
AU  - Meyer R
FAU - Hetzer, Roland
AU  - Hetzer R
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplantation
JT  - Transplantation
JID - 0132144
RN  - MU72812GK0 (Creatine)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Blood Urea Nitrogen
MH  - Creatine/blood
MH  - Female
MH  - *Heart Valve Prosthesis/statistics & numerical data
MH  - Humans
MH  - Kidney Function Tests
MH  - Male
MH  - Middle Aged
MH  - *Organ Transplantation
MH  - Survival Rate
MH  - Time Factors
EDAT- 2007/09/19 09:00
MHDA- 2007/10/18 09:00
CRDT- 2007/09/19 09:00
PHST- 2007/09/19 09:00 [pubmed]
PHST- 2007/10/18 09:00 [medline]
PHST- 2007/09/19 09:00 [entrez]
AID - 00007890-200709150-00005 [pii]
AID - 10.1097/01.tp.0000279005.85046.a6 [doi]
PST - ppublish
SO  - Transplantation. 2007 Sep 15;84(5):592-7. doi: 10.1097/01.tp.0000279005.85046.a6.