PMID- 17889187
OWN - NLM
STAT- MEDLINE
DCOM- 20071113
LR  - 20070924
IS  - 0041-1345 (Print)
IS  - 0041-1345 (Linking)
VI  - 39
IP  - 7
DP  - 2007 Sep
TI  - Clinical evolution of heart transplantation in patients with previous valvular 
      cardiomyopathy.
PG  - 2355-6
AB  - OBJECTIVE: Heart transplantation (HT) due to valvular cardiomyopathy is rare, 
      namely, about 3% of cases in the Registry of the International Society for Heart 
      and Lung Transplantation (ISHLT). Usually, these patients present some risk 
      factors such as previous valvular operations and pulmonary hypertension. Since 
      there are few studies in the literature, we retrospectively analyzed our early 
      and long-term results. MATERIALS AND METHODS: We studied our experience in 22 HT 
      cases for valvular cardiomyopathy (9.3% of our total experience), namely, 12 men 
      and 10 women, of overall mean age of 52.6 +/- 10 years. Five patients had mitral; 
      8, aortic; and 1, tricuspid valve disease; 7 had double valve disease and 1, 
      triple valve disease. Nineteen patients (87%) had been operated previously 
      between 1 and 4 times. The mean ejection fraction was 23% +/- 7.3% and the mean 
      New York Heart Association (NYHA) functional class was 3.7. Fifty-three percent 
      of the patients had pulmonary hypertension. Two patients were operated as an 
      emergency "O." We used the standard HT technique. RESULTS: Four patients (18%) 
      were reoperated due to hemorrhage. The hospital mortality was 2 cases (9%). 
      Another patients (9%) died on follow-up due to cardiac allograft vasculopathy. 
      All surviving patients have been followed to the end of 2006. The mean follow-up 
      has been 72 +/- 53 months. They are functional class I or II. CONCLUSIONS: HT for 
      this indication was more frequent in our experience than in the Registry of the 
      ISHLT. The immediate and long-term results were good, with an 82% mean survival 
      at 6 years. HT can be a good treatment for patients with valvular cardiomyopathy 
      and bad ventricular function and/or multiple valvular reoperations.
FAU - Rotela Samaniego, J A
AU  - Rotela Samaniego JA
AD  - Hospital Universitario de Bellvitge, University of Barcelona, IDIBELL, Barcelona, 
      Spain.
FAU - Castells, E
AU  - Castells E
FAU - Manito, N
AU  - Manito N
FAU - Roca, J
AU  - Roca J
FAU - Toscano, J
AU  - Toscano J
FAU - Calbet, J M
AU  - Calbet JM
FAU - Saura, E
AU  - Saura E
FAU - Fontanillas, C
AU  - Fontanillas C
FAU - Benito, M
AU  - Benito M
FAU - Granados, J
AU  - Granados J
FAU - Miralles, A
AU  - Miralles A
FAU - Rabasa, J M
AU  - Rabasa JM
FAU - Ortiz, D
AU  - Ortiz D
FAU - Toral, D
AU  - Toral D
FAU - Rullan, C
AU  - Rullan C
FAU - Ventura, J L
AU  - Ventura JL
FAU - Esplugas, E
AU  - Esplugas E
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Transplant Proc
JT  - Transplantation proceedings
JID - 0243532
SB  - IM
MH  - Adult
MH  - Cardiomyopathies/*etiology/surgery
MH  - Female
MH  - Heart Function Tests
MH  - Heart Transplantation/mortality/*physiology
MH  - Heart Valve Diseases/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Survival Analysis
MH  - Survivors
MH  - Treatment Outcome
EDAT- 2007/09/25 09:00
MHDA- 2007/11/14 09:00
CRDT- 2007/09/25 09:00
PHST- 2007/09/25 09:00 [pubmed]
PHST- 2007/11/14 09:00 [medline]
PHST- 2007/09/25 09:00 [entrez]
AID - S0041-1345(07)00896-2 [pii]
AID - 10.1016/j.transproceed.2007.07.062 [doi]
PST - ppublish
SO  - Transplant Proc. 2007 Sep;39(7):2355-6. doi: 10.1016/j.transproceed.2007.07.062.