PMID- 17895543
OWN - NLM
STAT- MEDLINE
DCOM- 20071207
LR  - 20190819
IS  - 1346-9843 (Print)
IS  - 1346-9843 (Linking)
VI  - 71
IP  - 10
DP  - 2007 Oct
TI  - Changes in left ventricular function and dimension after surgical ventricular 
      restoration with or without concomitant mitral valve procedure.
PG  - 1516-20
AB  - BACKGROUND: An association of mitral regurgitation (MR) with ischemic 
      cardiomyopathy (I-CMP) increases the risk of heart failure and its surgical 
      management remains controversial. METHODS AND RESULTS: Between July 2001 and June 
      2006, a total of 49 patients with I-CMP underwent surgical ventricular 
      restoration (SVR) and coronary revascularization with or without concomitant 
      mitral annuloplasty (MAP). The mean age was 59.8 years, and all patients had New 
      York Heart Association (NYHA) class III or IV heart failure (mean left 
      ventricular ejection fraction (LVEF) = 24.8%). Nineteen patients had MR >grade 3 
      (MR group). SVR and coronary artery bypass grafting were performed in all 
      patients, and concomitant MAP was performed in the MR group. Echocardiography was 
      performed preoperatively, postoperatively, and at mean of 19 months after 
      operation. Preoperative left ventricular (LV) end-diastolic and end-systolic 
      dimensions, left atrial volume index, and MR grade were statistically 
      significantly increased in the MR group. On the early postoperative 
      echocardiogram, mean LVEF was significantly improved, with reduction of LV 
      dimensions, in both groups; however, at follow up, these parameters were more 
      significantly improved in the MR group, but unchanged in non-MR group, reaching 
      almost the same levels as the non-MR group. CONCLUSION: In patients with I-CMP, 
      MR increases early and late mortality; however, after SVR and concomitant MAP, LV 
      function seems to continuously improve with more significant reduction in the LV 
      dimensions than in the non-MR group.
FAU - Lee, Sak
AU  - Lee S
AD  - Department of Thoracic and Cardiovascular Surgery, Yonsei University College of 
      Medicine, 134 Shinchon-dong, Seodaemoon-gu, Seol 120-752, Republic of Korea.
FAU - Chang, Byung-Chul
AU  - Chang BC
FAU - Youn, Young-Nam
AU  - Youn YN
FAU - Kwak, Young-Lan
AU  - Kwak YL
FAU - Yoo, Kyung-Jong
AU  - Yoo KJ
LA  - eng
PT  - Comparative Study
PT  - Journal Article
PL  - Japan
TA  - Circ J
JT  - Circulation journal : official journal of the Japanese Circulation Society
JID - 101137683
SB  - IM
MH  - Aged
MH  - Cardiac Surgical Procedures/*methods
MH  - Electrocardiography
MH  - Female
MH  - Follow-Up Studies
MH  - Heart Ventricles/*pathology/*surgery
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Mitral Valve/*surgery
MH  - Mitral Valve Insufficiency/etiology/surgery
MH  - Myocardial Ischemia/complications/surgery
MH  - Retrospective Studies
MH  - Stroke Volume/physiology
MH  - Treatment Outcome
MH  - Ventricular Function, Left/*physiology
EDAT- 2007/09/27 09:00
MHDA- 2007/12/08 09:00
CRDT- 2007/09/27 09:00
PHST- 2007/09/27 09:00 [pubmed]
PHST- 2007/12/08 09:00 [medline]
PHST- 2007/09/27 09:00 [entrez]
AID - JST.JSTAGE/circj/71.1516 [pii]
AID - 10.1253/circj.71.1516 [doi]
PST - ppublish
SO  - Circ J. 2007 Oct;71(10):1516-20. doi: 10.1253/circj.71.1516.