PMID- 17896505 OWN - NLM STAT- MEDLINE DCOM- 20150606 LR - 20181201 IS - 1000-1182 (Print) IS - 1000-1182 (Linking) VI - 25 IP - 4 DP - 2007 Aug TI - [Effect of platelet-rich plasma and latissimus dorsi myofascia with blood vessel on vascularization of tissue engineered bone in dogs]. PG - 408-11 AB - OBJECTIVE: To study the effect of platelet-rich plasma (PRP) and latissimus dorsi myofascia with blood vessel on vascularization of tissue engineered bone in dogs. METHODS: Bone marrow stromal cells (BMSCs) were isolated from iliac bone of dogs. PRP was obtained from the same dog. And demineralized bone matrix (DBM) were prepared from homologuous bone. ABCD 4 areas were divided on the back of dog. PRP/BMSCs/DBM was implanted around the vessels of lattisimus dorsi muscle in the A. PRP/BMSCs/DBM wrapped by superficial fascia in the B. BMSCs/DBM was implanted around vessels of lattisimus dorsi muscle in the C. BMSCs/DBM wrapped by superficial fascia in the D area of the same dog. 4, 8, 12 weeks after implantation, gross specimen and histology examination were made. RESULTS: Osteogenesis and blood vessel formation results were A>B>C>D area. CONCLUSION: The results suggested that the PRP and latissimus dorsi myofascia with blood vessels could promote calcification and vascularization in tissue-engineered bone. FAU - Li, Ning-yi AU - Li NY AD - Dept. of Oral and Maxillofacial Surgery, The Affiliated Hospital of Medical College, College of Stomatology, Qingdao University, Qingdao 266003, China. FAU - Chen, Li-qiang AU - Chen LQ FAU - Chen, Tao AU - Chen T FAU - Jin, Xiao-ming AU - Jin XM FAU - Yuan, Rong-tao AU - Yuan RT LA - chi PT - Journal Article PL - China TA - Hua Xi Kou Qiang Yi Xue Za Zhi JT - Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology JID - 9422648 RN - 0 (Biocompatible Materials) SB - IM MH - Animals MH - Biocompatible Materials MH - Bone and Bones MH - Dogs MH - Mesenchymal Stem Cells MH - Osteogenesis MH - *Platelet-Rich Plasma MH - Superficial Back Muscles MH - *Tissue Engineering EDAT- 2007/09/28 09:00 MHDA- 2015/06/07 06:00 CRDT- 2007/09/28 09:00 PHST- 2007/09/28 09:00 [pubmed] PHST- 2015/06/07 06:00 [medline] PHST- 2007/09/28 09:00 [entrez] PST - ppublish SO - Hua Xi Kou Qiang Yi Xue Za Zhi. 2007 Aug;25(4):408-11.