PMID- 17896737
OWN - NLM
STAT- MEDLINE
DCOM- 20071025
LR  - 20200205
IS  - 0008-4263 (Print)
IS  - 1920-7476 (Electronic)
IS  - 0008-4263 (Linking)
VI  - 98
IP  - 4
DP  - 2007 Jul-Aug
TI  - Newborn screening by tandem mass spectrometry: ethical and social issues.
PG  - 284-6
AB  - Emerging technologies like Tandem Mass Spectrometry (TMS) enable multiple tests 
      on a single blood sample and allow the expansion of Newborn Screening (NBS) to 
      include various metabolic diseases. Introducing TMS for NBS raises important 
      social and ethical questions: what are the criteria for adding disorders to 
      screening panels? What evidence justifies expansion of screening? How can equity 
      in NBS access and standards be ensured? How can policy standards be set, given 
      the multiplicity of stakeholders? To address emerging issues, policy-makers, 
      patient advocates, clinicians and researchers had a workshop during the 2005 
      Garrod Symposium. The participants received a summary of the discussion and 
      understood the workshop's goal was to provide a basis for further discussion. 
      This article contributes to this ongoing discussion. Several proposed 
      recommendations assert the centrality of including social and ethical issues in 
      the assessment of whether or not to introduce TMS. The article outlines five key 
      recommendations for advancing the NBS agenda: national public health leadership; 
      transparency; increased national consistency in NBS strategy, including minimum 
      standards; collaboration between the federal and provincial/territorial 
      governments and diverse stakeholders; and supporting research and/or programs 
      based on effectiveness, which integrate ethical and social issues into 
      assessment.
FAU - Avard, Denise
AU  - Avard D
AD  - Centre de recherche en droit public, Universite de Montreal, C.P. 6128, succ. 
      Centre-ville, Montreal, QC H3C 3J7. denise.avard@umontreal.ca
FAU - Vallance, Hilary
AU  - Vallance H
FAU - Greenberg, Cheryl
AU  - Greenberg C
FAU - Potter, Beth
AU  - Potter B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Can J Public Health
JT  - Canadian journal of public health = Revue canadienne de sante publique
JID - 0372714
SB  - IM
MH  - Canada
MH  - Health Policy
MH  - Humans
MH  - Infant, Newborn
MH  - National Health Programs
MH  - Neonatal Screening/*ethics/methods
MH  - *Social Justice
MH  - *Tandem Mass Spectrometry
PMC - PMC6975779
EDAT- 2007/09/28 09:00
MHDA- 2007/10/27 09:00
PMCR- 2008/07/01
CRDT- 2007/09/28 09:00
PHST- 2007/09/28 09:00 [pubmed]
PHST- 2007/10/27 09:00 [medline]
PHST- 2007/09/28 09:00 [entrez]
PHST- 2008/07/01 00:00 [pmc-release]
AID - BF03405404 [pii]
AID - 10.1007/BF03405404 [doi]
PST - ppublish
SO  - Can J Public Health. 2007 Jul-Aug;98(4):284-6. doi: 10.1007/BF03405404.