PMID- 17921853
OWN - NLM
STAT- MEDLINE
DCOM- 20071127
LR  - 20111006
IS  - 1077-4114 (Print)
IS  - 1077-4114 (Linking)
VI  - 29
IP  - 10
DP  - 2007 Oct
TI  - Human herpesvirus 6 (HHV-6)-associated pleurisy after unrelated cord blood 
      transplantation in children with chemotherapy-resistant malignant Lymphoma.
PG  - 709-12
AB  - Two children, 5 and 10 years of age, received unrelated cord blood 
      transplantation (CBT) for malignant lymphoma. Both of them suffered from pleurisy 
      with and without interstitial pneumonitis after transplantation. By the 
      quantitative real-time polymerase chain reaction, human herpesvirus 6 (HHV-6) 
      variant B DNA was detected in pleural effusion. This is the first report of 
      HHV-6-associated pleurisy after hematopoietic stem cell transplantation. 
      HHV-6-associated pleurisy should be considered as a complication after 
      hematopoietic stem cell transplantation even in the absence of pneumonitis. 
      Quantitative polymerase chain reaction is a useful tool for rapid detection of 
      viral DNA, which may facilitate precise diagnosis and appropriate treatment.
FAU - Suminoe, Aiko
AU  - Suminoe A
AD  - Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, 
      Higashi-ku, Fukuoka 812-8582, Japan. aikosu@mailserver.med.kyushu-u.ac.jp
FAU - Matsuzaki, Akinobu
AU  - Matsuzaki A
FAU - Koga, Yuhki
AU  - Koga Y
FAU - Kusuhara, Koichi
AU  - Kusuhara K
FAU - Hara, Toshiro
AU  - Hara T
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - United States
TA  - J Pediatr Hematol Oncol
JT  - Journal of pediatric hematology/oncology
JID - 9505928
RN  - 0 (DNA, Viral)
SB  - IM
MH  - Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
MH  - Child
MH  - Child, Preschool
MH  - Cord Blood Stem Cell Transplantation/*adverse effects
MH  - DNA, Viral/genetics
MH  - *Drug Resistance, Neoplasm
MH  - Female
MH  - Herpesvirus 6, Human/*isolation & purification
MH  - Humans
MH  - Lymphoma/complications/*drug therapy
MH  - Male
MH  - Pleurisy/therapy/*virology
MH  - Polymerase Chain Reaction
MH  - Roseolovirus Infections/therapy/*virology
EDAT- 2007/10/09 09:00
MHDA- 2007/12/06 09:00
CRDT- 2007/10/09 09:00
PHST- 2007/10/09 09:00 [pubmed]
PHST- 2007/12/06 09:00 [medline]
PHST- 2007/10/09 09:00 [entrez]
AID - 00043426-200710000-00007 [pii]
AID - 10.1097/MPH.0b013e318142b50d [doi]
PST - ppublish
SO  - J Pediatr Hematol Oncol. 2007 Oct;29(10):709-12. doi: 
      10.1097/MPH.0b013e318142b50d.