PMID- 17923745
OWN - NLM
STAT- MEDLINE
DCOM- 20080122
LR  - 20220309
IS  - 1011-8934 (Print)
IS  - 1598-6357 (Electronic)
IS  - 1011-8934 (Linking)
VI  - 22 Suppl
IP  - Suppl
DP  - 2007 Sep
TI  - Primary pulmonary Ewing's sarcoma/primitive neuroectodermal tumor in a 
      67-year-old man.
PG  - S159-63
AB  - Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), 
      which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is 
      the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron 
      emission tomography confirmed the mass to have a primary pulmonary origin. The 
      mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 
      immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization 
      (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 
      22q12 rearrangement. The diagnosis was confirmed both pathologically and 
      genetically. The mass lesion was resected, and the patient is currently 
      undergoing chemotherapy.
FAU - Lee, Yoon Young
AU  - Lee YY
AD  - Department of Family Medicine, Korea University, College of Medicine, Seoul, 
      Korea.
FAU - Kim, Do Hoon
AU  - Kim DH
FAU - Lee, Ji Hye
AU  - Lee JH
FAU - Choi, Jong Sang
AU  - Choi JS
FAU - In, Kwang Ho
AU  - In KH
FAU - Oh, Yu Whan
AU  - Oh YW
FAU - Cho, Kyung Hwan
AU  - Cho KH
FAU - Roh, Yong Kyun
AU  - Roh YK
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Korea (South)
TA  - J Korean Med Sci
JT  - Journal of Korean medical science
JID - 8703518
RN  - 0 (Calmodulin-Binding Proteins)
RN  - 0 (EWSR1 protein, human)
RN  - 0 (RNA-Binding Protein EWS)
RN  - 0 (RNA-Binding Proteins)
SB  - IM
MH  - Aged
MH  - Calmodulin-Binding Proteins/genetics
MH  - Chromosome Breakage
MH  - Chromosomes, Human, Pair 22/genetics
MH  - Diagnosis, Differential
MH  - Humans
MH  - Immunohistochemistry
MH  - In Situ Hybridization, Fluorescence
MH  - Lung Neoplasms/*diagnosis/genetics/metabolism/pathology
MH  - Male
MH  - Neuroectodermal Tumors, Primitive, 
      Peripheral/*diagnosis/genetics/metabolism/pathology
MH  - RNA-Binding Protein EWS
MH  - RNA-Binding Proteins/genetics
MH  - Sarcoma, Ewing/*diagnosis/genetics/metabolism/pathology
PMC - PMC2694395
EDAT- 2007/12/06 09:00
MHDA- 2008/01/23 09:00
PMCR- 2007/09/01
CRDT- 2007/12/06 09:00
PHST- 2007/12/06 09:00 [pubmed]
PHST- 2008/01/23 09:00 [medline]
PHST- 2007/12/06 09:00 [entrez]
PHST- 2007/09/01 00:00 [pmc-release]
AID - 200709s159 [pii]
AID - 10.3346/jkms.2007.22.S.S159 [doi]
PST - ppublish
SO  - J Korean Med Sci. 2007 Sep;22 Suppl(Suppl):S159-63. doi: 
      10.3346/jkms.2007.22.S.S159.