PMID- 17927804 OWN - NLM STAT- MEDLINE DCOM- 20080221 LR - 20230124 IS - 1600-6135 (Print) IS - 1600-6135 (Linking) VI - 7 IP - 12 DP - 2007 Dec TI - Cellulitis revealing a cryptococcosis-related immune reconstitution inflammatory syndrome in a renal allograft recipient. PG - 2826-8 AB - Immune reconstitution inflammatory syndrome (IRIS) has rarely been described in the course of disseminated cryptococcosis in solid organ transplant recipients. We report here the case of a renal transplant recipient who developed severe cellulitis in the context of Cryptococcus neoformans-associated IRIS while undergoing reduction of his immunosuppressive therapy. IRIS appeared concomitantly with a dramatic increase of blood CD4+ T cells (94-460/mm(3)) and required the administration of a short-term steroid therapy to resolve. FAU - Lanternier, F AU - Lanternier F AD - Service des Maladies Infectieuses et Tropicales Hopital Necker-Enfants Malades, Universite Paris V Centre d'Infectiologie Necker-Pasteur, Paris, Cedex 15, France. FAU - Chandesris, M-O AU - Chandesris MO FAU - Poiree, S AU - Poiree S FAU - Bougnoux, M-E AU - Bougnoux ME FAU - Mechai, F AU - Mechai F FAU - Mamzer-Bruneel, M-F AU - Mamzer-Bruneel MF FAU - Viard, J-P AU - Viard JP FAU - Galmiche-Rolland, L AU - Galmiche-Rolland L FAU - Lecuit, M AU - Lecuit M FAU - Lortholary, O AU - Lortholary O LA - eng PT - Case Reports PT - Journal Article DEP - 20071010 PL - United States TA - Am J Transplant JT - American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons JID - 100968638 RN - 0 (Adrenal Cortex Hormones) RN - 0 (Antifungal Agents) RN - 0 (Immunosuppressive Agents) SB - IM MH - Adrenal Cortex Hormones/therapeutic use MH - Antifungal Agents/therapeutic use MH - Cellulitis/*diagnosis/immunology/*microbiology MH - Cryptococcosis/*complications/*diagnosis/immunology MH - Cryptococcus neoformans/immunology MH - Humans MH - Immune Reconstitution Inflammatory Syndrome/*complications/*diagnosis/immunology MH - Immunosuppressive Agents/therapeutic use MH - Kidney Transplantation/*immunology MH - Male MH - Middle Aged MH - Opportunistic Infections/complications/diagnosis/immunology MH - Transplantation, Homologous EDAT- 2007/10/12 09:00 MHDA- 2008/02/22 09:00 CRDT- 2007/10/12 09:00 PHST- 2007/10/12 09:00 [pubmed] PHST- 2008/02/22 09:00 [medline] PHST- 2007/10/12 09:00 [entrez] AID - S1600-6135(22)12569-4 [pii] AID - 10.1111/j.1600-6143.2007.01994.x [doi] PST - ppublish SO - Am J Transplant. 2007 Dec;7(12):2826-8. doi: 10.1111/j.1600-6143.2007.01994.x. Epub 2007 Oct 10.