PMID- 17928196
OWN - NLM
STAT- MEDLINE
DCOM- 20080925
LR  - 20220318
IS  - 1097-6795 (Electronic)
IS  - 0894-7317 (Linking)
VI  - 21
IP  - 6
DP  - 2008 Jun
TI  - Significance of the distal to proximal coronary flow velocity ratio by 
      transthoracic Doppler echocardiography for diagnosis of proximal left coronary 
      artery stenosis.
PG  - 756-60
AB  - OBJECTIVE: This study was designed to evaluate the significance of accelerated 
      coronary flow velocity in the proximal left coronary artery by transthoracic 
      Doppler echocardiography for detecting coronary stenosis. METHODS: Seventy 
      subjects with suspected coronary artery disease underwent successful coronary 
      flow velocity measurement in both proximal and distal lesions by transthoracic 
      Doppler echocardiography and coronary angiography. RESULTS: On the basis of the 
      coronary angiography results, 23 patients had significant (> or =50%) stenosis in 
      the proximal left coronary artery (Group S) and 47 patients had no stenosis 
      (Group N). The distal averaged diastolic peak velocity to proximal averaged 
      diastolic peak velocity ratio (DAPAR) in Group S was significantly lower than 
      that in Group N. A cutoff value of DAPAR < or = 0.5 for DAPAR predicted 
      significant coronary stenosis with a sensitivity of 91% and a specificity of 72%. 
      CONCLUSION: Measurement of the DAPAR by transthoracic Doppler echocardiography is 
      a promising method in the noninvasive diagnosis of stenosis in the proximal left 
      coronary artery lesion.
FAU - Okayama, Hideki
AU  - Okayama H
AD  - Division of Cardiology, Department of Integrated Medicine and Informatics, Ehime 
      University Graduate School of Medicine, Toon, Japan. hiokayam@m.ehime-u.ac.jp
FAU - Nishimura, Kazuhisa
AU  - Nishimura K
FAU - Saito, Makoto
AU  - Saito M
FAU - Inoue, Katsuji
AU  - Inoue K
FAU - Hiasa, Go
AU  - Hiasa G
FAU - Sumimoto, Takumi
AU  - Sumimoto T
FAU - Ogimoto, Akiyoshi
AU  - Ogimoto A
FAU - Ohtsuka, Tomoaki
AU  - Ohtsuka T
FAU - Shigematsu, Yuji
AU  - Shigematsu Y
FAU - Higaki, Jitsuo
AU  - Higaki J
LA  - eng
PT  - Evaluation Study
PT  - Journal Article
DEP - 20071010
PL  - United States
TA  - J Am Soc Echocardiogr
JT  - Journal of the American Society of Echocardiography : official publication of the 
      American Society of Echocardiography
JID - 8801388
SB  - IM
MH  - Aged
MH  - Blood Flow Velocity
MH  - Coronary Angiography
MH  - Coronary Circulation
MH  - Coronary Stenosis/*diagnostic imaging/*physiopathology
MH  - Coronary Vessels/*diagnostic imaging/*physiopathology
MH  - *Echocardiography, Doppler, Color
MH  - Feasibility Studies
MH  - Female
MH  - *Hemodynamics
MH  - Humans
MH  - Male
EDAT- 2007/10/12 09:00
MHDA- 2008/09/26 09:00
CRDT- 2007/10/12 09:00
PHST- 2007/02/15 00:00 [received]
PHST- 2007/10/12 09:00 [pubmed]
PHST- 2008/09/26 09:00 [medline]
PHST- 2007/10/12 09:00 [entrez]
AID - S0894-7317(07)00676-1 [pii]
AID - 10.1016/j.echo.2007.08.052 [doi]
PST - ppublish
SO  - J Am Soc Echocardiogr. 2008 Jun;21(6):756-60. doi: 10.1016/j.echo.2007.08.052. 
      Epub 2007 Oct 10.