PMID- 17940807
OWN - NLM
STAT- MEDLINE
DCOM- 20080626
LR  - 20211020
IS  - 0931-041X (Print)
IS  - 0931-041X (Linking)
VI  - 23
IP  - 4
DP  - 2008 Apr
TI  - Diabetic nephropathy in children and adolescents.
PG  - 507-25
AB  - Type 1 diabetes mellitus (T1DM) commonly occurs in childhood or adolescence, 
      although the rising prevalence of type 2 diabetes mellitus (T2DM) in these age 
      groups is now being seen worldwide. Diabetic nephropathy (DN) develops in 15-20% 
      of subjects with T1DM and in similar or higher percentage of T2DM patients, 
      causing increased morbidity and premature mortality. Although overt DN or kidney 
      failure caused by either type of diabetes are very uncommon during childhood or 
      adolescence, diabetic kidney disease in susceptible patients almost certainly 
      begins soon after disease onset and may accelerate during adolescence, leading to 
      microalbuminuria or incipient DN. Therefore, all diabetics warrant ongoing 
      assessment of kidney function and screening for the earliest manifestations of 
      renal injury. Pediatric health care professionals ought to understand about risk 
      factors, strategy for prevention, method for screening, and treatment of early 
      DN. This review considers each form of diabetes separately, including natural 
      history, risk factors for development, screening for early manifestations, and 
      strategy recommended for prevention and treatment of DN in children and 
      adolescents.
FAU - Bogdanovic, Radovan
AU  - Bogdanovic R
AD  - The Institute of Mother and Child Healthcare of Serbia Dr Vukan Cupic, Belgrade, 
      Serbia. maloun@eunet.yu
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20071017
PL  - Germany
TA  - Pediatr Nephrol
JT  - Pediatric nephrology (Berlin, Germany)
JID - 8708728
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Diabetes Mellitus, Type 1/*complications/pathology/therapy
MH  - Diabetes Mellitus, Type 2/*complications/pathology/therapy
MH  - Diabetic Nephropathies/*etiology/pathology/prevention & control
MH  - Humans
MH  - Mass Screening
MH  - Risk Factors
RF  - 247
EDAT- 2007/10/18 09:00
MHDA- 2008/06/27 09:00
CRDT- 2007/10/18 09:00
PHST- 2007/04/07 00:00 [received]
PHST- 2007/07/12 00:00 [accepted]
PHST- 2007/07/09 00:00 [revised]
PHST- 2007/10/18 09:00 [pubmed]
PHST- 2008/06/27 09:00 [medline]
PHST- 2007/10/18 09:00 [entrez]
AID - 10.1007/s00467-007-0583-2 [doi]
PST - ppublish
SO  - Pediatr Nephrol. 2008 Apr;23(4):507-25. doi: 10.1007/s00467-007-0583-2. Epub 2007 
      Oct 17.