PMID- 17941191 OWN - NLM STAT- MEDLINE DCOM- 20080102 LR - 20161124 IS - 0914-5087 (Print) IS - 0914-5087 (Linking) VI - 50 IP - 3 DP - 2007 Sep TI - Mitral annulus displacement measured by tissue-tracking method with Doppler-tissue images is a useful marker of the severity of heart failure. PG - 159-66 AB - OBJECTIVES: This study investigated whether the measurement of mitral annulus displacement by the tissue-tracking method with Doppler-tissue images can provide more accurate information on the severity of heart failure compared to conventional methods, such as left ventricular ejection fraction (LVEF). BACKGROUND: Impaired left ventricular function is an important predictor of poor prognosis. Although LVEF has been used to assess left ventricular function, such indicators do not necessarily correlate well to clinical variables such as New York Heart Association (NYHA) functional class or plasma brain natriuretic peptide (BNP) concentration. METHODS: In 90 subjects with or without various heart diseases, mitral annulus displacement was measured by the tissue-tracking method with Doppler-tissue images and the correlations evaluated with NYHA functional class, plasma BNP concentration, left ventricular mass index and Tei index. RESULTS: Mitral annulus displacement by the tissue-tracking method with Doppler-tissue images was well correlated with NYHA functional class and plasma BNP concentration. LVEF was also correlated with these clinical variables, but significantly more weakly. Furthermore, mitral annulus displacement by the tissue-tracking method with Doppler-tissue images was correlated with left ventricular mass index and Tei index, which indicate left ventricular systolic and diastolic function. CONCLUSIONS: The present study suggests that mitral annulus displacement measured by our technique is a useful and reliable method for assessing the severity of heart failure. FAU - Ito, Koji AU - Ito K AD - Department of Cardiology, Kyushu Kosei-Nenkin Hospital, Kitakyushu. FAU - Noma, Mitsuru AU - Noma M FAU - Mohri, Masahiro AU - Mohri M FAU - Abe, Kohtaro AU - Abe K FAU - Yamamoto, Umpei AU - Yamamoto U FAU - Kikuchi, Kan AU - Kikuchi K FAU - Miyata, Kenji AU - Miyata K FAU - Origuchi, Hideki AU - Origuchi H FAU - Yamamoto, Hideo AU - Yamamoto H FAU - Tajimi, Tsukasa AU - Tajimi T FAU - Kikuchi, Yutaka AU - Kikuchi Y LA - eng PT - Comparative Study PT - Journal Article PL - Netherlands TA - J Cardiol JT - Journal of cardiology JID - 8804703 RN - 114471-18-0 (Natriuretic Peptide, Brain) SB - IM MH - Adolescent MH - Adult MH - Aged MH - Aged, 80 and over MH - Echocardiography MH - Female MH - Heart Failure/*diagnostic imaging/physiopathology MH - Heart Ventricles/physiopathology MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/*diagnostic imaging MH - Natriuretic Peptide, Brain/blood MH - Stroke Volume EDAT- 2007/10/19 09:00 MHDA- 2008/01/03 09:00 CRDT- 2007/10/19 09:00 PHST- 2007/10/19 09:00 [pubmed] PHST- 2008/01/03 09:00 [medline] PHST- 2007/10/19 09:00 [entrez] PST - ppublish SO - J Cardiol. 2007 Sep;50(3):159-66.