PMID- 17948027
OWN - NLM
STAT- MEDLINE
DCOM- 20080304
LR  - 20211020
IS  - 1350-9047 (Print)
IS  - 1476-5403 (Electronic)
IS  - 1350-9047 (Linking)
VI  - 15
IP  - 1
DP  - 2008 Jan
TI  - Interactions of tumor cells with dendritic cells: balancing immunity and 
      tolerance.
PG  - 39-50
AB  - Dendritic cells (DCs) are antigen-presenting cells specialized to initiate and 
      maintain immunity and tolerance. DCs initiate immune responses in a manner that 
      depends on signals they receive from pathogens, surrounding cells and their 
      products. Most tumors are infiltrated by DCs. Thus, interactions between DCs and 
      dying tumor cells may determine the balance between immunity and tolerance to 
      tumor cells. In addition, DCs also display non-immunologic effects on tumors and 
      the tumor microenvironment. Therefore, improved understanding of the cross talk 
      between tumor cells and DCs may suggest new approaches to improve cancer therapy.
FAU - Dhodapkar, M V
AU  - Dhodapkar MV
AD  - Laboratory of Tumor Immunology and Immunotherapy, The Rockefeller University, 
      1230 York Avenue, New York, NY 10021, USA. dhodapm@rockefeller.edu
FAU - Dhodapkar, K M
AU  - Dhodapkar KM
FAU - Palucka, A K
AU  - Palucka AK
LA  - eng
GR  - K08 AI054375/AI/NIAID NIH HHS/United States
GR  - CA 106802/CA/NCI NIH HHS/United States
GR  - AI 054375/AI/NIAID NIH HHS/United States
GR  - CA109465/CA/NCI NIH HHS/United States
GR  - R01 CA106802/CA/NCI NIH HHS/United States
GR  - R01 CA109465/CA/NCI NIH HHS/United States
GR  - R01 CA089440/CA/NCI NIH HHS/United States
GR  - R01 CA078846/CA/NCI NIH HHS/United States
GR  - R01 CA106802-04/CA/NCI NIH HHS/United States
GR  - CA 078846/CA/NCI NIH HHS/United States
GR  - R01 CA 089440/CA/NCI NIH HHS/United States
GR  - AT 02779/AT/NCCIH NIH HHS/United States
GR  - P01 CA 084514/CA/NCI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20071019
PL  - England
TA  - Cell Death Differ
JT  - Cell death and differentiation
JID - 9437445
RN  - 0 (Cytokines)
RN  - 0 (Receptors, Cell Surface)
RN  - 0 (Toll-Like Receptors)
SB  - IM
MH  - Animals
MH  - Cell Death
MH  - Cytokines/immunology/*metabolism
MH  - Dendritic Cells/*immunology/*physiology
MH  - Humans
MH  - Immune Tolerance
MH  - Immunity, Cellular
MH  - Immunotherapy
MH  - Neoplasms/*immunology/pathology/*physiopathology/therapy
MH  - Receptors, Cell Surface/immunology/*metabolism
MH  - Signal Transduction
MH  - T-Lymphocytes, Regulatory/immunology
MH  - Toll-Like Receptors/immunology/*metabolism
PMC - PMC2762352
MID - NIHMS36990
EDAT- 2007/10/20 09:00
MHDA- 2008/03/05 09:00
PMCR- 2009/10/15
CRDT- 2007/10/20 09:00
PHST- 2007/10/20 09:00 [pubmed]
PHST- 2008/03/05 09:00 [medline]
PHST- 2007/10/20 09:00 [entrez]
PHST- 2009/10/15 00:00 [pmc-release]
AID - 4402247 [pii]
AID - 10.1038/sj.cdd.4402247 [doi]
PST - ppublish
SO  - Cell Death Differ. 2008 Jan;15(1):39-50. doi: 10.1038/sj.cdd.4402247. Epub 2007 
      Oct 19.