PMID- 17952279 OWN - NLM STAT- MEDLINE DCOM- 20080501 LR - 20190815 IS - 0004-282X (Print) IS - 0004-282X (Linking) VI - 65 IP - 3B DP - 2007 Sep TI - Cooling modifies mixed median and ulnar palmar studies in carpal tunnel syndrome. PG - 779-82 AB - Temperature is an important and common variable that modifies nerve conduction study parameters in practice. Here we compare the effect of cooling on the mixed palmar median to ulnar negative peak-latency difference (PMU) in electrodiagnosis of carpal tunnel syndrome (CTS). Controls were 22 subjects (19 women, mean age 42.1 years, 44 hands). Patients were diagnosed with mild symptomatic CTS (25 women, mean age 46.6 years, 34 hands). PMU was obtained at the usual temperature, >32 degrees C, and after wrist/hand cooling to <27 degrees C in ice water. After cooling, there was a significantly greater increase in PMU and mixed ulnar palmar latency in patients versus controls. We concluded that cooling significantly modifies the PMU. We propose that the latencies of compressed nerve overreact to cooling and that this response could be a useful tool for incipient CTS electrodiagnosis. There was a significant latency overreaction of the ulnar nerve to cooling in CTS patients. We hypothesize that subclinical ulnar nerve compression is associated with CTS. FAU - Araujo, Rogerio Gayer Machado de AU - Araujo RG AD - Neuromuscular Investigation Laboratory, Department of Neurological Sciences, Faculdade de Medicina de Sao Jose do Rio Preto, Rua Luiz Antonio da Silveira 1661, 15025-020 Sao Jose do Rio Preto, SP, Brazil. FAU - Kouyoumdjian, Joao Aris AU - Kouyoumdjian JA LA - eng PT - Journal Article PL - Germany TA - Arq Neuropsiquiatr JT - Arquivos de neuro-psiquiatria JID - 0125444 SB - IM MH - Adult MH - Body Temperature/physiology MH - Carpal Tunnel Syndrome/*diagnosis/physiopathology MH - Case-Control Studies MH - *Cold Temperature MH - Electromyography/methods MH - Female MH - Humans MH - Male MH - Median Nerve/*physiopathology MH - Middle Aged MH - Neural Conduction/*physiology MH - Prospective Studies MH - Reaction Time MH - Severity of Illness Index MH - Ulnar Nerve/*physiopathology EDAT- 2007/10/24 09:00 MHDA- 2008/05/02 09:00 CRDT- 2007/10/24 09:00 PHST- 2007/01/26 00:00 [received] PHST- 2007/05/30 00:00 [accepted] PHST- 2007/10/24 09:00 [pubmed] PHST- 2008/05/02 09:00 [medline] PHST- 2007/10/24 09:00 [entrez] AID - S0004-282X2007000500008 [pii] AID - 10.1590/s0004-282x2007000500008 [doi] PST - ppublish SO - Arq Neuropsiquiatr. 2007 Sep;65(3B):779-82. doi: 10.1590/s0004-282x2007000500008.